Clinical evidence that Asperger's disorder is a mild form of autism

被引:14
|
作者
Ritvo, Riva Ariella [1 ]
Ritvo, Edward R. [2 ]
Guthrie, Donald [2 ]
Ritvo, Max J. [3 ]
机构
[1] Yale Univ, Sch Med, Yale Child Study Ctr, New Haven, CT 06520 USA
[2] Univ Calif Los Angeles, Sch Med, Inst Neuropsychiat, Los Angeles, CA 90024 USA
[3] Harvard Westlake Sch, Los Angeles, CA 90077 USA
关键词
D O I
10.1016/j.comppsych.2007.06.010
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
Objective: The aim of this study is to obtain clinical evidence to test the hypothesis that Asperger's disorder (AD) is a mild form of autism (AU). Method: A 78-item Likert scale (the RAADS) was administered to 25 adults with AD and 19 with AU (ages, 18-65 years) to assess presence, type, and duration of symptoms. Results: The following results were found: (a) subjects with AD and AU have similar symptoms throughout adulthood (responses to 72 of 78 questions were not significantly different); (b) subjects with AD had a significantly fewer total number of symptoms; (c) subjects with AD reported nonsignificantly fewer symptoms in the DSM-V-TR domainsof social interaction and repetitive patterns of behavior; and (d) subjects with AD had significantly fewer symptoms in the cominunication domain. Conclusions: The data support the hypothesis that AD is a mild form of AU, and that they share a common etiology and developmental neuropathology. It appears warranted in future diagnostic manuals to incorporate AU and AD into I diagnostic category such as, "Autism Spectrum Disorder, (with modifiers, severe, moderate, mild, atypical, and Asperger's type)." (c) 2008 Elsevier Inc. All rights reserved.
引用
收藏
页码:1 / 5
页数:5
相关论文
共 50 条
  • [1] Comparison of clinical symptoms in autism and Asperger's disorder
    Eisenmajer, R
    Prior, M
    Leekam, S
    Wing, L
    Gould, J
    Welham, M
    Ong, B
    [J]. JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY, 1996, 35 (11): : 1523 - 1531
  • [2] Autism and Asperger's disorder: A neurobehavioural approach to clinical definition
    Rinehart, NJ.
    [J]. AUSTRALIAN JOURNAL OF PSYCHOLOGY, 2006, 58 : 186 - 186
  • [3] SACCADE ADAPTATION IN AUTISM AND ASPERGER'S DISORDER
    Johnson, B. P.
    Rinehart, N. J.
    White, O.
    Millist, L.
    Fielding, J.
    [J]. NEUROSCIENCE, 2013, 243 : 76 - 87
  • [4] A clinical and neurobehavioural review of high-functioning autism and Asperger's disorder
    Rinehart, NJ
    Bradshaw, JL
    Brereton, AV
    Tonge, BJ
    [J]. AUSTRALIAN AND NEW ZEALAND JOURNAL OF PSYCHIATRY, 2002, 36 (06): : 762 - 770
  • [5] A neurobehavioural and clinical comparison of children with high-functioning autism and Asperger's disorder
    Rinehart, N. J.
    Bradshaw, J. L.
    Brenton, A., V
    Tonge, B. J.
    [J]. AUSTRALIAN JOURNAL OF PSYCHOLOGY, 2001, 53 : 172 - 172
  • [6] Recognition memory in asperger's disorder and high functioning autism
    D'Angelo, EJ
    Ritholz, M
    [J]. CLINICAL NEUROPSYCHOLOGIST, 1999, 13 (02): : 225 - 225
  • [7] An investigation into sleep characteristics of children with autism and Asperger's Disorder
    Patzold, LM
    Richdale, AL
    Tonge, BJ
    [J]. JOURNAL OF PAEDIATRICS AND CHILD HEALTH, 1998, 34 (06) : 528 - 533
  • [8] Neuropsychological and soft sign findings in autism and Asperger's disorder
    Aronowitz, B
    [J]. BIOLOGICAL PSYCHIATRY, 1998, 43 : 4S - 4S
  • [9] The classification of autism, Asperger's syndrome, and pervasive developmental disorder
    Szatmari, P
    [J]. CANADIAN JOURNAL OF PSYCHIATRY-REVUE CANADIENNE DE PSYCHIATRIE, 2000, 45 (08): : 731 - 738
  • [10] Brief Report: Biochemical Correlates of Clinical Impairment in High Functioning Autism and Asperger’s Disorder
    Natalia M. Kleinhans
    Todd Richards
    Kurt E. Weaver
    Olivia Liang
    Geraldine Dawson
    Elizabeth Aylward
    [J]. Journal of Autism and Developmental Disorders, 2009, 39 : 1079 - 1086