Cartilage disease diagnosis by conventional and polarization-sensitive optical coherence tomography

被引：2

作者：

Xie, TQ ^{[1
]}

Guo, SG ^{[1
]}

Rao, B ^{[1
]}

Chen, ZP ^{[1
]}

Peavy, GM ^{[1
]}

机构：

[1] Univ Calif Irvine, Beckman Laser Inst, Irvine, CA 92612 USA

来源：

Coherence Domain Optical Methods and Optical Coherence Tomography in Biomedicine IX | 2005年 / 5690卷

关键词：

optical coherence tomography; polarization sensitive; birefringence; noninvasive; biomedical optical imaging; cartilage; diagnosis; degenerative joint disease;

D O I：

10.1117/12.591129

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

In this paper, the conventional and polarization sensitive optical coherence tomography (PS-OCT) were used to image bovine articular cartilage and diagnose degenerative joint disease. The results showed that these 2 D cross-sectional OCT images that can cover an area of 6x2.8mm(2) (limited by scope size) with a traverse resolution of 12 mu m and an axial resolution of 10 pm could assess the microstructure of articular cartilage and differentiate the abnormalities in structure. The results were confirmed by their histology. Compared to conventional OCT, PS-OCT could provide depth-resolved strokes parameter images, which reflect tissue birefringence. Both conventional and PS-OCT have high efficiency and sensitivity of osteoarthritis and cartilage injury and disease diagnosis.

引用

页码：556 / 562

页数：7

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