Bisbenzylisoquinoline Alkaloids from Nelumbo nucifera

被引：59
|
作者：
Itoh, Atsuko [1 ]
Saitoh, Tomomi [1 ]
Tani, Kaori [1 ]
Uchigaki, Misaki [1 ]
Sugimoto, Yumi [2 ]
Yamada, Jun [2 ]
Nakajima, Hiroshi [3 ]
Ohshiro, Hideo [4 ]
Sun, Schujian [4 ]
Tanahashi, Takao [1 ]
机构：
[1] Kobe Pharmaceut Univ, Higashinada Ku, Kobe, Hyogo 6588558, Japan
[2] Yokohama Coll Pharm, Totsuka Ku, Yokohama, Kanagawa 2450066, Japan
[3] Osaka City Univ, Res Ctr Ind Innovat, Sumiyoshi Ku, Osaka 5588585, Japan
[4] Shanghai Univ Tradit Chinese Med, Kita Ku, Osaka 5300047, Japan
来源：
CHEMICAL & PHARMACEUTICAL BULLETIN | 2011年 / 59卷 / 08期
关键词：
Nelumbo nucifera; Nelumbonaceae; bisbenzylisoquinoline alkaloid; nelumboferine; nelumborine; NEFERINE; EMBRYO; ISOLIENSININE; GAERTN; LOTI; MICE;
D O I：
10.1248/cpb.59.947
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
From the embryos of the seeds of Nelumbo nucifera, three bisbenzylisoquinoline alkaloids, nelumboferine and nelumborines A and B, were isolated along with four known compounds, neferine, liensinine, isoliensinine and anisic acid. The structures of the new alkaloids were determined mainly by spectroscopic methods.
引用
收藏
页码：947 / 951
页数：5
相关论文
共 50 条
  • [1] The Cytoprotective and Anti-cancer Potential of Bisbenzylisoquinoline Alkaloids from Nelumbo nucifera
    Manogaran, Prasath
    Beeraka, Narasimha Murthy
    Padma, Viswanadha Vijaya
    CURRENT TOPICS IN MEDICINAL CHEMISTRY, 2019, 19 (32) : 2940 - 2957
  • [2] Structurally Diverse Bisbenzylisoquinoline Alkaloids with Antiadipogenic Activity through PPARγ Downregulation from the Embryo of Nelumbo nucifera Seeds
    Zhang, Peiliang
    Li, Jiadong
    Shi, Jiyao
    Cheng, Zhihong
    Wu, Tao
    JOURNAL OF NATURAL PRODUCTS, 2024, 87 (04): : 1013 - 1022
  • [3] STUDIES ON ALKALOIDS OF NELUMBO-NUCIFERA GAERTN .16. ALKALOIDS OF NELUMBO-NUCIFERA
    KUNITOMO, J
    YOSHIKAW.Y
    TANAKA, S
    IMORI, Y
    ISOI, K
    PHYTOCHEMISTRY, 1973, 12 (03) : 699 - 701
  • [4] ALKALOIDS FROM EMBRYO OF THE SEED OF NELUMBO-NUCIFERA
    NISHIBE, S
    TSUKAMOTO, H
    KINOSHITA, H
    KITAGAWA, S
    SAKUSHIMA, A
    JOURNAL OF NATURAL PRODUCTS, 1986, 49 (03): : 547 - 548
  • [5] An updated review on pharmacological properties of neferine-A bisbenzylisoquinoline alkaloid from Nelumbo nucifera
    Priya, Lohanathan Bharathi
    Huang, Chih-Yang
    Hu, Rouh-Mei
    Balasubramanian, Balamuralikrishnan
    Baskaran, Rathinasamy
    JOURNAL OF FOOD BIOCHEMISTRY, 2021, 45 (12)
  • [6] Micellar Electrokinetic Chromatography Using a Cationic Surfactant for Rapid Separation and Determination of Bisbenzylisoquinoline Alkaloids from Embryo of the Seed of Nelumbo nucifera Gaertn
    Zhu, Jinhua
    Zhang, Huige
    Qi, Shengda
    Chen, Xingguo
    Hu, Zhide
    CHROMATOGRAPHIA, 2011, 73 (5-6) : 535 - 540
  • [7] Benzylisoquinoline alkaloids from the embryo of Nelumbo nucifera and their antioxidant effects
    Zhou, Zhanrong
    Wang, Xin
    Wang, Hongqing
    Shao, Hongjie
    Sun, Junhua
    Chen, Ruoyun
    Kang, Jie
    FITOTERAPIA, 2025, 180
  • [8] Micellar Electrokinetic Chromatography Using a Cationic Surfactant for Rapid Separation and Determination of Bisbenzylisoquinoline Alkaloids from Embryo of the Seed of Nelumbo nucifera Gaertn
    Jinhua Zhu
    Huige Zhang
    Shengda Qi
    Xingguo Chen
    Zhide Hu
    Chromatographia, 2011, 73 : 535 - 540
  • [9] Synthesis and Pharmacological Activity of Alkaloids from Embryo of Lotus, Nelumbo nucifera
    Nishimura, Katsumi
    Horii, Shinji
    Tanahashi, Takao
    Sugirnoto, Yumi
    Yamada, Jun
    CHEMICAL & PHARMACEUTICAL BULLETIN, 2013, 61 (01) : 59 - 68
  • [10] Flavonoid glycosides and alkaloids from the embryos of Nelumbo nucifera seeds and their antioxidant activity
    Jiang, Xi-Lan
    Wang, Lun
    Wang, En-Jun
    Zhang, Guo-Lin
    Chen, Bin
    Wang, Ming-Kui
    Li, Fu
    FITOTERAPIA, 2018, 125 : 184 - 190
12345