Kaempferol Enhanced the Intracellular Thioredoxin System in Normal Cultured Human Keratinocytes

被引：4
|
作者：
Sugahara, Misato [1 ]
Nakanishi, Jotaro [1 ]
Katsuta, Yuji [1 ]
机构：
[1] Shiseido Res Ctr, Tsuzuki Ku, Yokohama, Kanagawa 2248558, Japan
来源：
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY | 2010年 / 74卷 / 08期
关键词：
kaempferol; quercetin; thioredoxin; OXIDATIVE STRESS; FLAVONOIDS; APOPTOSIS; REDUCTASE; CELLS; GENE;
D O I：
10.1271/bbb.100166
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The effects of kaempferol on redox-associated enzymes in normal human keratinocytes were studied. It enhanced the gene expression of thioredoxin reductase 1 and thioredoxin. Flavonols had higher ability to induce the expression of these genes than the other antioxidants and the other flavonoids tested. Furthermore, kaempferol and quercetin increased the activity of thioredoxin reductase in normal human keratinocytes.
引用
收藏
页码：1701 / 1703
页数：3
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