Molecular pathology of non-small-cell lung cancer

被引：43
|
作者：
Breuer, RHJ [1 ]
Postmus, PE [1 ]
Smit, EF [1 ]
机构：
[1] Free Univ Amsterdam, Med Ctr, Dept Pulmonol, NL-1007 MB Amsterdam, Netherlands
来源：
RESPIRATION | 2005年 / 72卷 / 03期
关键词：
carcinogenesis; lung cancer; molecular pathology; non-small-cell lung cancer; oncogenes; tumor suppressor genes;
D O I：
10.1159/000085376
中图分类号：
R56 [呼吸系及胸部疾病];
学科分类号：
摘要：
The molecular basis of lung carcinogenesis must be understood more fully and exploited to enhance survival rates of patients suffering from lung cancer. In this review we will discuss the major molecular alterations that occur in lung cancer. Emphasis is placed on alterations that occur early during carcinogenesis since they might be relevant for future screening programs. Finally we will shortly review new approaches that are used to study the molecular pathology of lung cancer and how they can be applied in a clinical setting. Copyright (C) 2005 S. Karger AG, Basel.
引用
收藏
页码：313 / 330
页数：18
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