The prolyl hydroxylase enzymes that act as oxygen sensors regulating destruction of hypoxia-inducible factor α

被引：23
|
作者：
Willam, C [1 ]
Nicholls, LG [1 ]
Ratcliffe, PJ [1 ]
Pugh, CW [1 ]
Maxwell, PH [1 ]
机构：
[1] Wellcome Trust Ctr Human Genet, Oxford OX3 7BN, England
来源：
ADVANCES IN ENZYME REGULATION, VOL 44 | 2004年 / 44卷
关键词：
D O I：
10.1016/j.advenzreg.2003.11.017
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
引用
收藏
页码：75 / 92
页数：18
相关论文
共 50 条
  • [1] Evidence for the slow reaction of hypoxia-inducible factor prolyl hydroxylase 2 with oxygen
    Flashman, Emily
    Hoffart, Lee M.
    Hamed, Refaat B.
    Bollinger, J. Martin, Jr.
    Krebs, Carsten
    Schofield, Christopher J.
    FEBS JOURNAL, 2010, 277 (19) : 4089 - 4099
  • [2] Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitors and Iron Metabolism
    Ogawa, Chie
    Tsuchiya, Ken
    Maeda, Kunimi
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 24 (03)
  • [3] Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitors for Anemia in CKD
    Parfrey, Patrick
    NEW ENGLAND JOURNAL OF MEDICINE, 2021, 385 (25): : 2390 - 2391
  • [4] Mucosal protection by hypoxia-inducible factor prolyl hydroxylase inhibition
    Robinson, Andreas
    Keely, Simon
    Karhausen, Joern
    Gerich, Mark E.
    Furuta, Glenn T.
    Colgan, Sean P.
    GASTROENTEROLOGY, 2008, 134 (01) : 145 - 155
  • [5] Hypoxia-inducible factor prolyl hydroxylase enzyme inhibitors: ready for primetime?
    Macdougall, Iain C.
    CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION, 2022, 31 (05): : 399 - 405
  • [6] FDA approves first hypoxia-inducible factor prolyl hydroxylase inhibitor
    Asher Mullard
    Nature Reviews Drug Discovery, 2023, 22 : 173 - 173
  • [7] Hypoxia-inducible factor prolyl hydroxylase inhibitors in kidney transplant recipients
    Ogata, Masatomo
    Miyauchi, Takamasa
    Sakurai, Yuko
    Murata, Marie
    Shinoda, Kazunobu
    Shibagaki, Yugo
    Yazawa, Masahiko
    CLINICAL KIDNEY JOURNAL, 2022, 15 (05) : 1024 - 1026
  • [8] FDA approves first hypoxia-inducible factor prolyl hydroxylase inhibitor
    Mullard, Asher
    NATURE REVIEWS DRUG DISCOVERY, 2023, 22 (03) : 173 - 173
  • [9] Mucosal protection by hypoxia-inducible factor (HIF) prolyl hydroxylase inhibition
    Keeley, Simon
    Furuta, Glenn T.
    Colgan, Sean P.
    FASEB JOURNAL, 2008, 22
  • [10] Inhibition of Hypoxia-Inducible Factor Prolyl Hydroxylase Domain Oxygen Sensors: Tricking the Body into Mounting Orchestrated Survival and Repair Responses
    Rabinowitz, Michael H.
    JOURNAL OF MEDICINAL CHEMISTRY, 2013, 56 (23) : 9369 - 9402
12345