Synthesis of 4-substituted 4-arylpiperidines

被引：10
|
作者：
Harriman, GCB [1 ]
Shao, JX [1 ]
Luly, JR [1 ]
机构：
[1] Millennium Pharmaceut Inc, Cambridge, MA 02139 USA
来源：
TETRAHEDRON LETTERS | 2000年 / 41卷 / 46期
关键词：
D O I：
10.1016/S0040-4039(00)01610-5
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Several novel 4-substituted 4-arylpiperidines were synthesized. The chemistry leading to 4-(4-chlorophenyl)-4-fluoropiperidine (6), 4-azido-4-(4-chlorophenyl)piperidine (7) and 4-(4-chlorophenyl)-4methylpiperidine (8) is described. (C) 2000 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码：8853 / 8856
页数：4
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