Synthesis of fluorous and nonfluorous polycyclic systems by one-pot, double intramolecular 1,3-dipolar cycloaddition of azomethine ylides

被引：54
|
作者：
Zhang, W
Lu, YM
Geib, S
机构：
[1] Univ Pittsburgh, Appl Res Ctr, Fluorous Technol Inc, Pittsburgh, PA 15238 USA
[2] Univ Pittsburgh, Dept Chem, Pittsburgh, PA 15260 USA
来源：
ORGANIC LETTERS | 2005年 / 7卷 / 11期
关键词：
D O I：
10.1021/ol0507773
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Under microwave irradiation, a one-pot, double intramolecular [3 + 2]-cycloaddition reaction of azomethine ylides leads to formation of a novel hexacyclic ring system. The major diastereomer is isolated, and its stereochemistry is determined by X-ray crystal structure analysis.
引用
收藏
页码：2269 / 2272
页数：4
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