Marine natural products: chemical and biological potential of seaweeds and their endophytic fungi

被引：21

作者：

Leandrini de Oliveira, Ana Ligia ^{[1
]}

de Felicio, Rafael ^{[1
]}

Debonsi, Hosana Maria ^{[1
]}

机构：

[1] Univ Sao Paulo, Dept Quim & Fis, Nucleo Pesquisas Prod Nat & Sintet, Fac Ciencias Farmaceuticas Ribeirao Preto, BR-14049 Ribeirao Preto, SP, Brazil

来源：

REVISTA BRASILEIRA DE FARMACOGNOSIA-BRAZILIAN JOURNAL OF PHARMACOGNOSY | 2012年 / 22卷 / 04期

关键词：

algicolous fungi; endophytic fungi; marine algae; marine natural products; TYROSINE KINASE INHIBITOR; RED ALGA; BROWN ALGA; IN-VITRO; CADINANE SESQUITERPENE; SECONDARY METABOLITES; XANTHONE DERIVATIVES; ALGICOLOUS ISOLATE; KAINIC ACID; DITERPENE;

D O I：

10.1590/S0102-695X2012005000083

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Marine natural products have currently been recognized as the most promising source of bioactive substances for drug discovery research. In this review, extraordinary metabolites from marine algae species are illustrated, as well as approaches for their isolation and determination of their biological properties and pharmaceutical potential. Furthermore, marine endophytic microorganisms (from marine algae) are presented as a new subject for extensive investigation to find novel natural products, which make them a potentially rich and innovative source for new drug candidates.

引用

页码：906 / 920

页数：15

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