Histone deacetylase inhibitors LBH589 and LAQ824 deplete Ezh2 and associated Polycomb Repressive Complex 2/3 proteins resulting in downregulation of HOXA9 and MEIS1 expression in human acute leukemia cells.

被引:0
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作者
Fiskus, W
Pranpat, M
Bali, P
Kumaraswamy, S
Boyapalle, S
Rocha, K
Balasis, M
Atadja, P
Bhalla, K
机构
[1] H Lee Moffitt Canc Ctr & Res Inst, Tampa, FL USA
[2] Novartis Pharmaceut, Cambridge, MA USA
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D O I
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中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
2482
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页码:697A / 697A
页数:1
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