Syntheses of 2-Aroyl 3-Aryl Benzofuran and Benzothiophenes

被引：0
|
作者：
Umareddy, Pailla [1 ]
Arava, Veera Reddy [1 ]
机构：
[1] R&D Ctr Suven Life Sci Ltd, Plot 18,Phase 3, Hyderabad 500055, India
来源：
JOURNAL OF HETEROCYCLIC CHEMISTRY | 2018年 / 55卷 / 11期
关键词：
SOLID-PHASE SYNTHESIS; RECEPTOR ANTAGONISTS; DERIVATIVES; HETEROCYCLES; INHIBITORS; DISCOVERY;
D O I：
10.1002/jhet.3287
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A novel method has been developed for the synthesis of 6-methoxy 2-aroyl 3-aryl benzofuran and benzothiophenes from 2-(3-Methoxy-phenoxy or thioxy)-1-phenyl-ethanone and substituted benzoyl chloride through Friedel-Crafts benzoylation and cyclization reaction. The method accepts a variety of functional groups on the benzoyl chloride.
引用
收藏
页码：2640 / 2646
页数：7
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