Differential catalytic UDP-glucuronosyltransferase (UGT) activities in human liver and colon are not the result of differences in UGT1A protein expression

被引：0
|
作者：
Strassburg, CP
Nguyen, N
Manns, MP
Tukey, RH
机构：
[1] Univ Calif San Diego, Dept Pharmacol, La Jolla, CA 92093 USA
[2] Univ Calif San Diego, Ctr Canc, La Jolla, CA 92093 USA
[3] Med Hsch Hannover, Dept Gastroenterol & Hepatol, Hannover, Germany
来源：
HEPATOLOGY | 1998年 / 28卷 / 04期
关键词：
D O I：
暂无
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
879
引用
收藏
页码：382A / 382A
页数：1
相关论文
共 50 条
  • [1] Polymorphic expression of the UDP-glucuronosyltransferase UGT1A gene locus in human gastric epithelium
    Strassburg, CP
    Nguyen, N
    Manns, MP
    Tukey, RH
    MOLECULAR PHARMACOLOGY, 1998, 54 (04) : 647 - 654
  • [2] Interactions Between Human UDP-Glucuronosyltransferase (UGT) 2B7 and UGT1A Enzymes
    Fujiwara, Ryoichi
    Nakajima, Miki
    Oda, Shingo
    Yamanaka, Hiroyuki
    Ikushiro, Shin-Ichi
    Sakaki, Toshiyuki
    Yokoi, Tsuyoshi
    JOURNAL OF PHARMACEUTICAL SCIENCES, 2010, 99 (01) : 442 - 454
  • [3] Quantitative Analysis of UDP-Glucuronosyltransferase Ugt1a and Ugt2b mRNA Expression in the Rat Liver and Small Intestine: Sex and Strain Differences
    Kutsukake, Takaya
    Furukawa, Yoichi
    Ondo, Kyoko
    Gotoh, Saki
    Fukami, Tatsuki
    Nakajima, Miki
    DRUG METABOLISM AND DISPOSITION, 2019, 47 (01) : 38 - 44
  • [4] The Activity of Members of the UDP-Glucuronosyltransferase Subfamilies UGT1A and UGT2B is Impaired in Patients with Liver Cirrhosis
    Urs Duthaler
    Fabio Bachmann
    Agustos C. Ozbey
    Kenichi Umehara
    Neil Parrott
    Stephen Fowler
    Stephan Krähenbühl
    Clinical Pharmacokinetics, 2023, 62 : 1141 - 1155
  • [5] The Activity of Members of the UDP-Glucuronosyltransferase Subfamilies UGT1A and UGT2B is Impaired in Patients with Liver Cirrhosis
    Duthaler, Urs
    Bachmann, Fabio
    Ozbey, Agustos C.
    Umehara, Kenichi
    Parrott, Neil
    Fowler, Stephen
    Krahenbuhl, Stephan
    CLINICAL PHARMACOKINETICS, 2023, 62 (08) : 1141 - 1155
  • [6] Cloning and expression of human UDP-glucuronosyltransferase (UGT) 1A8
    Cheng, ZQ
    Radominska-Pandya, A
    Tephly, TR
    ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1998, 356 (02) : 301 - 305
  • [7] DIFFERENTIAL EXPRESSION OF ISOFORMS TO UDP-GLUCURONOSYLTRANSFERASE (UGT) IN RAT MODELS OF LIVER-INJURY
    DEBINSKI, HS
    DESMOND, PV
    LEE, S
    DANKS, J
    TEPHLEY, T
    MACKENZIE, P
    GASTROENTEROLOGY, 1993, 104 (04) : A893 - A893
  • [8] Hepatic microsomal UDP-glucuronosyltransferase (UGT) activities in the microminipig
    Higashi, Eriko
    Ando, Akihiro
    Iwano, Shunsuke
    Murayama, Norie
    Yamazaki, Hiroshi
    Miyamoto, Yohei
    BIOPHARMACEUTICS & DRUG DISPOSITION, 2014, 35 (06) : 313 - 320
  • [9] Monospecific antipeptide antibodies against human hepatic UDP-Glucuronosyltransferase]A subfamily (UGT1A) Isoforms
    Ikushiro, Shin-Ichi
    Emi, Yoshikazu
    Kato, Yoshihisa
    Yamada, Shizuo
    Sakaki, Toshiyuki
    DRUG METABOLISM AND PHARMACOKINETICS, 2006, 21 (01) : 70 - 74
  • [10] Expression of UDP-Glucuronosyltransferase 1A (UGT1A) in Bladder Cancer: Association with Prognosis and Regulation by Estrogen
    Izumi, K.
    Li, Y.
    Ishiguro, H.
    Zheng, Y.
    Yao, J. L.
    Netto, G. J.
    Miyamoto, H.
    MODERN PATHOLOGY, 2013, 26 : 220A - 220A
12345