Synthesis and structure of new heterocyclic derivatives of curcumin

被引:0
|
作者
Lozada, MC
Enríquez, RG
Lobato, CE
Ortíz, B
Soriano, M
Gnecco, D
Reynolds, WF
机构
[1] Univ Nacl Autonoma Mexico, Inst Chem, Mexico City 04510, DF, Mexico
[2] BUAP, Inst Sci, Ctr Chem, Puebla 72000, Mexico
[3] Univ Toronto, Dept Chem, Toronto, ON M5S 1A1, Canada
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中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
New heterocyclic derivatives of curcumin (3) of different ring size were synthesized by reaction of a key intermediate, 1,7-bis(4-acetoxy-3-methoxyphenyl)hepta-3,5-dione (5) with some bi-nucleophilic molecules. These new synthetic derivatives were obtained in good yields and the structure of all compounds was supported by MS, IR, 1D and 2D H-1 and C-13 NMR spectra and elemental analysis.
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页码:49 / 58
页数:10
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