DNA-photocleavage agents

被引:43
|
作者
Da Ros, T
Spalluto, G
Boutorine, AS
Bensasson, RV
Prato, M
机构
[1] Univ Trieste, Dipartimento Sci Farmaceut, I-34127 Trieste, Italy
[2] Museum Natl Hist Nat, CNRS UMR 8646, INSERM U 201, Biophys Lab, F-75231 Paris 05, France
关键词
D O I
10.2174/1381612013397140
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
This review describes recent advances in the development of DNA-photocleavage agents. Major mechanisms of photosensitized DNA photocleavage are presented and the most popular categories of compounds are considered, which include metal complexes and many organic functional derivatives. DNA-targeted conjugates of photosensitizers are also described and discussed.
引用
收藏
页码:1781 / 1821
页数:41
相关论文
共 50 条
  • [1] DNA-photocleavage activities of vanadium(V)-peroxo complexes
    Kwong, DWJ
    Chan, OY
    Wong, RNS
    Musser, SM
    Vaca, L
    Chan, SI
    [J]. INORGANIC CHEMISTRY, 1997, 36 (07) : 1276 - 1277
  • [2] DNA-Photocleavage Activities of Vanadium(V)-Peroxo Complexes
    Department of Chemistry, Hong Kong Baptist University, Kowloon Tong, Hong Kong
    不详
    不详
    不详
    [J]. Inorg. Chem., 7 (1276-1277):
  • [3] Synthesis, and DNA-binding and DNA-photocleavage properties of multiply charged porphyrins
    Wang, Kai
    Zhang, Zhi
    Wu, Lei
    Li, Zao-Ying
    [J]. CHEMISTRY & BIODIVERSITY, 2007, 4 (03) : 514 - 522
  • [4] Synthesis, Characterization, DNA-Binding, and DNA-Photocleavage Properties of RuII Complexes
    Tan, Lifeng
    Chen, Xuejiao
    Sheng, Jianliang
    [J]. AUSTRALIAN JOURNAL OF CHEMISTRY, 2009, 62 (12) : 1646 - 1654
  • [5] Theoretical studies on DNA-photocleavage efficiencies of Ru(II) polypyridyl complexes
    Miao, Ti-Fang
    Li, Shuang
    Chen, Jin-Can
    Wang, Na-Li
    Zheng, Kang-Cheng
    [J]. DALTON TRANSACTIONS, 2013, 42 (07) : 2463 - 2468
  • [6] Theoretical studies on DNA-photocleavage efficiencies and mechanisms of Ru(II) polypyridyl complexes
    Ti-Fang Miao
    Shuang Li
    Jin-Can Chen
    Fang Ma
    Kang-Cheng Zheng
    [J]. JBIC Journal of Biological Inorganic Chemistry, 2012, 17 : 1177 - 1185
  • [7] Theoretical studies on DNA-photocleavage efficiencies and mechanisms of Ru(II) polypyridyl complexes
    Miao, Ti-Fang
    Li, Shuang
    Chen, Jin-Can
    Ma, Fang
    Zheng, Kang-Cheng
    [J]. JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY, 2012, 17 (08): : 1177 - 1185
  • [8] Theoretical Studies on DNA-Photocleavage Efficiency and Mechanism of Functionalized Ru(II) Polypyridyl Complexes
    Miao, Ti-Fang
    Li, Jun
    Li, Shuang
    Wang, Na-Li
    [J]. JOURNAL OF PHYSICAL CHEMISTRY A, 2014, 118 (30): : 5692 - 5699
  • [9] Theoretical studies on the spectral and DNA-photocleavage properties of Co(III) and Ru(II) polypyridyl complexes
    Miao, Ti-Fang
    Li, Jun
    Liao, Si-Yan
    Mei, Juan
    Zheng, Kang-Cheng
    [J]. JOURNAL OF MOLECULAR STRUCTURE-THEOCHEM, 2010, 957 (1-3): : 108 - 113
  • [10] DNA- and RNA-binding and enhanced DNA-photocleavage properties of a ferrocenyl-containing ruthenium(II) complex
    Zhao, Xiao-Long
    Han, Mei-Jiao
    Zhang, An-Guo
    Wang, Ke-Zhi
    [J]. JOURNAL OF INORGANIC BIOCHEMISTRY, 2012, 107 (01) : 104 - 110