Ovarian mucinous cystadenocarcinoma with malignant mural nodules

被引:6
|
作者
Nakamura, E [1 ]
Shimizu, M [1 ]
Mikami, Y [1 ]
Kawai, J [1 ]
Manabe, T [1 ]
机构
[1] Kawasaki Med Sch, Dept Pathol, Okayama 7010192, Japan
关键词
mucinous cystadenocarcinoma; mural nodules; ovary;
D O I
10.1111/j.1440-1827.1998.tb03964.x
中图分类号
R36 [病理学];
学科分类号
100104 ;
摘要
A case of ovarian mucinous cystadenocarcinoma with malignant mural nodules is reported. The patient was a 28-year-old Japanese female (gravida 0, para 0) with a 2 year history of increasing abdominal fullness and edema of the lower extremity. Physical examination showed a large mass in the abdomen. An abdominal ultrasound and computed tomography demonstrated a multilocular cyst with a solid component. Lymph node and distant metastases were not found. These tests were followed by surgery. The resected right ovarian tumor measured 25 x 22 x 18cm. On cut sectioning, it was multilocular with multiple mural nodules. Microscopically, the cyst wall was lined with papillary infoldings of atypical mucinous epithelium (intestinal type). Nuclear stratification, cribriform and back-to-back glandular patterns and stromal invasion were observed. In addition, the solid area of the mural nodules showed spindle or polygonal cells with increased mitotic activity including atypical mitoses. Nuclear pleomorphism was marked. Necrosis and hemorrhage were also present. Reticulin stain showed these pleomorphic cell clusters circumscribed by reticulin fibers and these cells were immunoreactive for vimentin and p53.
引用
收藏
页码:645 / 648
页数:4
相关论文
共 50 条
  • [1] OVARIAN MUCINOUS CYSTADENOCARCINOMA WITH SARCOMA-LIKE MURAL NODULES
    HAMADA, T
    SASAGURI, T
    TANIMOTO, A
    ARIMA, N
    NAKANO, R
    MIYAYAMA, H
    SASAGURI, Y
    JOURNAL OF SURGICAL ONCOLOGY, 1995, 58 (03) : 201 - 207
  • [2] Ovarian mucinous cystadenocarcinoma with mural nodule
    Demirbag, R. Nilgun
    Oran, Gulbin
    Goksedef, Pinar Cilesiz
    Batmaz, Gonca Kolukfaki
    VIRCHOWS ARCHIV, 2007, 451 (02) : 494 - 494
  • [3] Malignant mural nodules of indeterminate differentiation in ovarian mucinous tumors
    Burga, AM
    Jones, M
    Tavassoli, FA
    LABORATORY INVESTIGATION, 2002, 82 (01) : 192A - 193A
  • [4] Ovarian Mucinous Tumor With Malignant Mural Nodules: Dedifferentiation or Collision?
    Desouki, Mohamed M.
    Khabele, Dineo
    Crispens, Marta A.
    Fadare, Oluwole
    INTERNATIONAL JOURNAL OF GYNECOLOGICAL PATHOLOGY, 2015, 34 (01) : 19 - 24
  • [5] Malignant mural nodules of indeterminate differentiation in ovarian mucinous tumors
    Burga, AM
    Jones, M
    Tavassoli, FA
    MODERN PATHOLOGY, 2002, 15 (01) : 192A - 193A
  • [6] IMMUNOHISTOLOGY OF A SARCOMATOUS MURAL NODULE IN AN OVARIAN MUCINOUS CYSTADENOCARCINOMA
    BRUIJN, JA
    SMIT, VTHBM
    QUE, DG
    FLEUREN, GJ
    INTERNATIONAL JOURNAL OF GYNECOLOGICAL PATHOLOGY, 1987, 6 (03) : 287 - 293
  • [7] IMMUNOHISTOCHEMICAL STUDY OF SARCOMA-LIKE MURAL NODULES IN A MUCINOUS CYSTADENOCARCINOMA OF THE OVARY
    MATIASGUIU, X
    ARANDA, I
    PRAT, J
    VIRCHOWS ARCHIV A-PATHOLOGICAL ANATOMY AND HISTOPATHOLOGY, 1991, 419 (02) : 89 - 92
  • [8] PANCREATIC MUCINOUS CYSTADENOCARCINOMA WITH PSEUDOSARCOMATOUS MURAL NODULES - A REPORT OF A CASE WITH IMMUNOHISTOCHEMICAL STUDY
    REGO, JAG
    RUVIRA, LV
    GARCIA, AA
    FREIJANES, MPS
    PENARANDA, JMS
    SOTO, JMR
    CANCER, 1991, 67 (02) : 494 - 498
  • [9] Primary retroperitoneal mucinous cystadenocarcinoma with mural nodules: a case report and literature review
    Kanayama, Tomoko
    Yoshino, Kiyoshi
    Enomoto, Takayuki
    Ohashi, Hiroshi
    Fujita, Masami
    Ueda, Yutaka
    Kimura, Toshihiro
    Kobayashi, Eiji
    Morii, Eiichi
    Kimura, Tadashi
    INTERNATIONAL JOURNAL OF CLINICAL ONCOLOGY, 2012, 17 (04) : 407 - 411
  • [10] Primary retroperitoneal mucinous cystadenocarcinoma with mural nodules: a case report and literature review
    Tomoko Kanayama
    Kiyoshi Yoshino
    Takayuki Enomoto
    Hiroshi Ohashi
    Masami Fujita
    Yutaka Ueda
    Toshihiro Kimura
    Eiji Kobayashi
    Eiichi Morii
    Tadashi Kimura
    International Journal of Clinical Oncology, 2012, 17 : 407 - 411