Cobalt-Catalyzed C-H Cyanation of Arenes and Heteroarenes

被引：275

作者：

Li, Jie ^{[1
]}

Ackermann, Lutz ^{[1
]}

机构：

[1] Univ Gottingen, Inst Organ & Biomol Chem, D-37077 Gottingen, Germany

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2015年 / 54卷 / 12期

基金：

欧洲研究理事会;

关键词：

C-H activation; cobalt; cyanides; heterocycles; synthetic methods; DIRECT ARYLATION; BOND FUNCTIONALIZATIONS; CARBON-HYDROGEN; ARYL BROMIDES; ALKYNES; HYDROARYLATION; COMPLEX; MILD; N; N-DIMETHYLFORMAMIDE; ACTIVATION;

D O I：

10.1002/anie.201409247

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Carboxylate assistance proved to be the key for the success of efficient cobalt(III)-catalyzed C-H cyanations. Thus, an in situ generated cationic cobalt complex was identified as a versatile catalyst for the site-selective synthesis of various aromatic and heteroaromatic nitriles with ample substrate scope.

引用

页码：3635 / 3638

页数：4

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