Expression of prostaglandin E2 receptor subtypes in the developing sheep brainstem

被引：14
|
作者：
Tai, TC
Lye, SJ
Adamson, SL
机构：
[1] Mt Sinai Hosp, Samuel Lunenfeld Res Inst, Program Dev & Fetal Hlth, Toronto, ON M5G 1X5, Canada
[2] Univ Toronto, Inst Med Sci, Toronto, ON M5S 1A8, Canada
[3] Univ Toronto, Dept Obstet, Toronto, ON M5S 1A8, Canada
[4] Univ Toronto, Dept Gynecol, Toronto, ON M5S 1A8, Canada
[5] Univ Toronto, Dept Physiol, Toronto, ON M5S 1A8, Canada
来源：
MOLECULAR BRAIN RESEARCH | 1998年 / 57卷 / 01期
基金：
英国医学研究理事会;
关键词：
fetus; newborn; adult; development; brain; EP;
D O I：
10.1016/S0169-328X(98)00072-2
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
Expression in sheep brain of EP transcripts and their ontogeny in the brainstem was determined using RT-PCR. Sheep EP subtypes showed high homology (> 80%) with other species. EP1, EP2, EP3 and EP4 were expressed in spinal cord, medulla, pens, diencephalon, hippocampus, pituitary, cortex and cerebellum of the fetal, newborn and adult sheep brain. Expression of all four peaked in the newborn, whereas fetal and adult expression were similar. A similar ontogeny suggests a common regulation. (C) 1998 Elsevier Science B.V. All rights reserved.
引用
收藏
页码：161 / 166
页数：6
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