Purpose of Review Carcinoid heart disease is a rare disorder that is associated with significant morbidity and mortality. In this review of the literature, we will present current concepts in diagnosis and management of carcinoid heart disease. Recent Findings Recent expert consensus guidelines highlight the role of echocardiography and screening with NT-proBNP for the evaluation of carcinoid heart disease. Advances in medical therapy along with better surgical outcomes highlight the experience and expertise that has been gained in the treatment of carcinoid heart disease. Summary Carcinoid heart disease occurs in patients with neuroendocrine tumors who have carcinoid syndrome. Serotonin appears to play a central role in the development of carcinoid heart disease. Cardiac biomarkers and multimodality imaging can be used to aid in screening and diagnosis. The mainstay of treatment of carcinoid heart disease is surgery.
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Univ Pittsburgh, Dept Med, Med Ctr, Pittsburgh, PA 15213 USABrown Univ, Dept Med, Warren Alpert Med Sch, Providence, RI 02903 USA
Diamantopoulos, Leonidas
Toumpanakis, Christos
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Royal Free Hosp NHS Fdn Trust, Ctr Gastroenterol, ENETS Ctr Excellence, Neuroendocrine Tumor Unit, London NW3 2QG, EnglandBrown Univ, Dept Med, Warren Alpert Med Sch, Providence, RI 02903 USA
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Royal Free Hosp, Neuroendocrine Tumour Unit, Pond St, London NW3 2QG, EnglandRoyal Free Hosp, Neuroendocrine Tumour Unit, Pond St, London NW3 2QG, England
Hayes, Aimee R.
Davar, Joseph
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Royal Free Hosp, Carcinoid Heart Dis Clin, Dept Cardiol, Pond St, London NW3 2QG, EnglandRoyal Free Hosp, Neuroendocrine Tumour Unit, Pond St, London NW3 2QG, England
Davar, Joseph
Caplin, Martyn E.
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Royal Free Hosp, Neuroendocrine Tumour Unit, Pond St, London NW3 2QG, EnglandRoyal Free Hosp, Neuroendocrine Tumour Unit, Pond St, London NW3 2QG, England
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Royal Free Hosp, Neuroendocrine Tumour Unit, Ctr Gastroenterol, London, EnglandRoyal Free Hosp, Neuroendocrine Tumour Unit, Ctr Gastroenterol, London, England
Laskaratos, Faidon-Marios
Davar, Joseph
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Royal Free Hosp, Carcinoid Heart Dis Clin, London, EnglandRoyal Free Hosp, Neuroendocrine Tumour Unit, Ctr Gastroenterol, London, England
Davar, Joseph
Toumpanakis, Christos
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Royal Free Hosp, Neuroendocrine Tumour Unit, Ctr Gastroenterol, London, EnglandRoyal Free Hosp, Neuroendocrine Tumour Unit, Ctr Gastroenterol, London, England