KPT-350, a Selective Inhibitor of Nuclear Export (SINE) Compound, Shows Efficacy in the Mouse Pilocarpine Model of Temporal Lobe Epilepsy

被引:0
|
作者
Tamir, Sharon
Cochran, Shelton
Lee, Margaret
Shacham, Sharon
Leclercq, Karine
Kaminski, Rafal
De Ryck, Marc
Kenda, Benoit
机构
关键词
D O I
暂无
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
S211
引用
收藏
页码:S67 / S67
页数:1
相关论文
共 50 条
  • [1] KPT-350, a selective inhibitor of nuclear export (SINE) compound, shows efficacy in the mouse pilocapine model of temporal lobe epilepsy
    Tamir, S.
    Cochran, S.
    Argueta, C.
    Lee, M.
    Shacham, S.
    Leclerq, K.
    Kaminski, R.
    De Ryck, M.
    Kenda, B.
    JOURNAL OF THE NEUROLOGICAL SCIENCES, 2017, 381 : 87 - 88
  • [2] Neuroprotective Effects of KPT-350, a Selective Inhibitor of Nuclear Export (SINE) Compound, in a Rodent Model of TBI
    Drolen, C.
    Tamir, S.
    Tajiri, N.
    Acosta, S. A.
    Lee, M.
    Shacham, S.
    Borlongan, C. V.
    CELL TRANSPLANTATION, 2016, 25 (04) : 755 - 755
  • [3] KPT-350, A Selective Inhibitor of Nuclear Export (SINE) Compound, Improves Behavioral and Histological Parameters in a Rat Model of Traumatic Brain Injury
    Tajiri, Naoki
    Acosta, Sandra
    Yu, Arun
    Kaneko, Yuji
    Tamir, Sharon
    Carlson, Robert
    Shacham, Sharon
    Borlongan, Cesar
    JOURNAL OF HEAD TRAUMA REHABILITATION, 2015, 30 (03) : E68 - E69
  • [4] Functional and Imaging Studies of the Selective Inhibitor of Nuclear Export (SINE) Compound KPT-350 in a Clinically Relevant Murine Model of Closed Head Injury (CHI)
    Drolen, Claire
    Wang, Haichen
    Venkatraman, Talaignair
    Fang, Chuan
    Tan, Yanli
    Tamir, Sharon
    Shacham, Sharon
    Lascola, Christopher
    Laskowitz, Daniel
    NEUROLOGY, 2016, 86
  • [5] KPT-350, A SELECTIVE INHIBITOR OF NUCLEAR EXPORT (SINE) COMPOUND, EFFECTIVELY REDUCES INTERFERON-ALPHA ACTIVATION AND AUTOREACTIVE PLASMA CELLS IN MURINE LUPUS
    Rangel-Moreno, J.
    Wang, W.
    Owen, T.
    Barnard, J.
    Klebanov, B.
    Landesman, Y.
    Tamir, S.
    Shacham, S.
    Anolik, J.
    ANNALS OF THE RHEUMATIC DISEASES, 2016, 75 : 283 - 283
  • [6] The selective inhibitor of nuclear export ( SINE) compound, KPT-350, exerts neuroprotective and anti-inflammatory activity in rat models of traumatic brain injury
    Tamir, Sharon
    Tajiri, Naoki
    Acosta, Sandra
    Lee, Margaret
    Kashyap, Trinayan
    Elloul, Sivan
    Carlson, Robert
    Landesman, Yosef
    Shacham, Sharon
    Borlongan, Cesario
    BRAIN INJURY, 2016, 30 (5-6) : 530 - 530
  • [7] KPT-350, a Selective Inhibitor of Nuclear Export (SINE) compound, reduces primary and secondary injury in core-impact and peri-impact TBI lesions
    Tamir, S.
    Tajiri, N.
    Acosta, S.
    Landesman, Y.
    Lee, M.
    Shacham, S.
    Borlongan, C.
    EUROPEAN JOURNAL OF NEUROLOGY, 2016, 23 : 732 - 733
  • [8] Synergistic antitumor effect of selinexor, a selective inhibitor of nuclear export (SINE) compound and panobinostat in a mouse model of multiple myeloma
    Elloul, Sivan
    Chang, Hua
    Klebanov, Boris
    Kashyap, Trinayan
    Werman, Maxwell
    Lee, Margaret
    Landesman, Yosef
    Shacham, Sharon
    Kauffman, Michael
    Friedlander, Sharon Y.
    CANCER RESEARCH, 2016, 76
  • [9] Synergistic antitumor effect of selinexor, a selective inhibitor of nuclear export (SINE) compound and trastuzumab in a mouse model of breast cancer
    Elloul, Sivan
    Chang, Hua Hua
    Klebanov, Boris
    Kashyap, Trinayan
    Werman, Maxwell
    Lee, Margaret
    Landesman, Yosef
    Shacham, Sharon
    Kauffman, Michael
    Friedlander, Sharon Y.
    CANCER RESEARCH, 2016, 76
  • [10] Pilocarpine model of temporal lobe epilepsy shows enhanced response to general anesthetics
    Long, Jennifer J. A.
    Shen, Bixia
    Luo, Tao
    Stewart, Lee
    McMurran, Thomas J. A.
    Leung, L. Stan
    EXPERIMENTAL NEUROLOGY, 2009, 219 (01) : 308 - 318