Targeted protection of proximal tubular cells by nanoparticle-enhanced delivery of a TLR9-antagonist

被引：7
|
作者：
Endre, Zoltan H. [1 ,2 ]
Erlich, Jonathan H. [1 ,2 ]
机构：
[1] Prince Wales Hosp, Dept Nephrol, Sydney, NSW, Australia
[2] Univ New South Wales, Prince Wales Clin Sch, Sydney, NSW, Australia
来源：
KIDNEY INTERNATIONAL | 2020年 / 98卷 / 01期
关键词：
INJURY;
D O I：
10.1016/j.kint.2020.04.024
中图分类号：
R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];
学科分类号：
1002 ; 100201 ;
摘要：
The kidney target site for injury that leads to acute kidney injury (AKI) is the proximal tubule. Nanoparticle-encapsulation enhanced delivery of a selective Toll-like receptor 9 antagonist to mouse proximal tubules and attenuated experimental ischemia-reperfusion injury in a mouse model of AKI. Copyright (C) 2020, International Society of Nephrology. Published by Elsevier Inc. All rights reserved.
引用
收藏
页码：48 / 50
页数：3
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