Synthesis and crystal structures of fluorinated indols as RNA analogues

被引:0
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作者
Bozilovic, J [1 ]
Bats, JW [1 ]
Engels, JW [1 ]
机构
[1] Goethe Univ Frankfurt, Inst Organ Chem, D-60439 Frankfurt, Germany
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中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Artificial indol nucleosides have been synthesized. We improved synthesis and crystal structures of fluorinated indols as RNA nucleosides. We crystallized two of synthesised nucleosides. All synthesised nucleosides are going to be incorporated in RNA oligonucleotides and UV-melting profiles and CD-spectra are going to be determined.
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页码:385 / 386
页数:2
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