Clindamycin Hypersensitivity and Management in a Case with Invasive Group A Streptococcal Cellulitis Caused by Chickenpox

Chickenpox is commonly known as a benign exenthamatous disease of childhood that causes vesicular rashes. Symptomatic therapy is usually adequate for chickenpox but in some cases secondary bacterial infections constitute the most common cause of morbidity in children. Primer varicella is an important predisposing factor for invasive group A streptococcal infection. In the treatment of invasive group A streptococcal infection generally accepted therapeutic management includes early administration of penicillin in combination with clindamycin, intravenous immunoglobulins and early surgical intervention. In this report we describe a patient who developed clindamycin hypersensitivity during invasive group A streptococcal cellulitis management.