Real-time treatment planning optimisation for brachytherapy

被引：0
|
作者：
Chatelain, S [1 ]
Thiran, JP [1 ]
Zilio, VO [1 ]
Bettler, MO [1 ]
Joneja, OP [1 ]
Chawla, R [1 ]
Popowski, Y [1 ]
机构：
[1] Swiss Fed Inst Technol, Signal Proc Inst, CH-1015 Lausanne, Switzerland
来源：
DFMA '05: FIRST INTERNATIONAL CONFERENCE ON DISTRIBUTED FRAMEWORKS FOR MULTIMEDIA APPLICATIONS, PROCEEDINGS | 2004年
关键词：
medical imaging; brachytherapy; image-guided treatment; computer-assisted intervention;
D O I：
暂无
中图分类号：
TP [自动化技术、计算机技术];
学科分类号：
0812 ;
摘要：
In this paper, we present an integrated system for real-time dose distribution calculation and treatment planning optimisation for brachytherapy of prostate cancer, with a special emphasis on the visual integration of the dosimetry and target images obtained from the open magnetic resonance system. This system involves a fast method to: calculate dose distributions of multiple concurrent radioactive sources, based on the combination of elements from a database of pre-calculated dose distribution; maps for single sources, combined linearly to provide the final dose distribution map. Simulated annealing, in conjunction with the inverse planning method, is used to determine the source dwell times at pre-selected locations in order to optimally irradiate the tumour while preserving the surrounding healthy tissues. This algorithm, implemented in FORTRAN, is integrated into a computer-assisted treatment planning tool, written in JAVA, using the runtime class and RMI API of Java. The whole system is now under clinical testing at the Geneva University Hospital.
引用
收藏
页码：303 / 307
页数：5
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