Value of 18-F-FDG PET/CT and CT in the Diagnosis of Indeterminate Adrenal Masses

被引：26
|
作者：
Launay, Nathalie [1 ,2 ]
Silvera, Stephane [1 ]
Tenenbaum, Florence [3 ]
Groussin, Lionel [2 ,4 ]
Tissier, Frederique [2 ,5 ]
Audureau, Etienne [2 ,6 ]
Vignaux, Olivier [1 ,2 ]
Dousset, Bertrand [2 ,7 ]
Bertagna, Xavier [2 ,4 ]
Legmann, Paul [1 ,2 ]
机构：
[1] Cochin Univ Hosp, Dept Radiol, F-75014 Paris, France
[2] Univ Paris 05, Sorbonne Paris Cite, F-75006 Paris, France
[3] Cochin Univ Hosp, Dept Nucl Med, F-75014 Paris, France
[4] Cochin Univ Hosp, Dept Endocrinol, F-75014 Paris, France
[5] Cochin Univ Hosp, Dept Anatomopathol, F-75014 Paris, France
[6] Hotel Dieu Univ Hosp, Dept Epidemiol & Biostat, F-75004 Paris, France
[7] Cochin Univ Hosp, Dept Digest & Endocrine Surg, F-75014 Paris, France
来源：
INTERNATIONAL JOURNAL OF ENDOCRINOLOGY | 2015年 / 2015卷
关键词：
TIME PAIR SELECTION; ADRENOCORTICAL CARCINOMA; IN-PHASE; LESIONS; MRI; ADENOMAS; TOMOGRAPHY; ACCURACY; PROTOCOL; FAT;
D O I：
10.1155/2015/213875
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
The purpose of this paper was to study the value of 18-FDG PET/CT and reassess the value of CT for the characterization of indeterminate adrenal masses. 66 patients with 67 indeterminate adrenal masses were included in our study. CT/MRI images and 18F-FDG PET/CT data were evaluated blindly for tumor morphology, enhancement features, apparent diffusion coefficient values, maximum standardized uptake values, and adrenal-to-liver maxSUV ratio. The study population comprised pathologically confirmed 16 adenomas, 19 metastases, and 32 adrenocortical carcinomas. Macroscopic fat was observed in 62.5% of the atypical adenomas at CT but not in malignantmasses. On 18F-FDGPET/CT, SUVmax and adrenal-to-livermaxSUVratio were significantly lower in adenomas than in malignant tumors. An SUVmax value of less than 3.7 or an adrenal-to-liver maxSUV ratio of less than 1.29 is highly predictive of benignity.
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页数：8
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