Potent in vitro and in vivo effects of EB-3D, a novel choline-kinase inhibitor in breast cancer

被引：0
|
作者：
Viola, Giampietro [1 ]
Mariotto, Elena [1 ]
Bortolozzi, Roberta [1 ]
Ronca, Roberto [2 ,3 ]
Cara, Luisa Carlota Lopez [4 ]
Entrena, Antonio [4 ]
Basso, Giuseppe [1 ]
机构：
[1] Univ Padua, Dept Womans & Childs Hlth, Padua, Italy
[2] Univ Brescia, Dipartimento Med Mol & Traslaz, Brescia, Italy
[3] Univ Brescia, Unita Oncol Sperimentale & Immunol, Brescia, Italy
[4] Univ Granada, Dept Med & Organ Chem, Sch Pharm, Granada, Spain
来源：
FASEB JOURNAL | 2016年 / 30卷
关键词：
D O I：
暂无
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
937.2
引用
收藏
页数：2
相关论文
共 50 条
  • [1] In vitro and in vivo pharmacological study of EB-3D: a novel choline kinase inhibitor for breast cancer treatment
    Mariotto, Elena
    Bortolozzi, Roberta
    Ronca, Roberto
    Lopez-Cara, Luisa C.
    Accordi, Benedetta
    Serafin, Valentina
    Basso, Giuseppe
    Viola, Giampietro
    [J]. CANCER RESEARCH, 2016, 76
  • [2] Choline Kinase Alpha Inhibition by EB-3D Triggers Cellular Senescence, Reduces Tumor Growth and Metastatic Dissemination in Breast Cancer
    Mariotto, Elena
    Viola, Giampietro
    Ronca, Roberto
    Persano, Luca
    Aveic, Sanja
    Bhujwalla, Zaver M.
    Mori, Noriko
    Accordi, Benedetta
    Serafin, Valentina
    Lopez-Cara, Luisa Carlota
    Bortolozzi, Roberta
    [J]. CANCERS, 2018, 10 (10):
  • [3] EB-3D a novel choline kinase inhibitor induces deregulation of the AMPK-mTOR pathway and apoptosis in leukemia T-cells
    Mariotto, Elena
    Bortolozzi, Roberta
    Volpin, Ilaria
    Carta, Davide
    Serafin, Valentina
    Accordi, Benedetta
    Basso, Giuseppe
    Luque Navarro, Pilar
    Carlota Lopez-Cara, Luisa
    Viola, Giampietro
    [J]. BIOCHEMICAL PHARMACOLOGY, 2018, 155 : 213 - 223
  • [4] Choline kinase inhibitors EB-3D and EB-3P interferes with lipid homeostasis in HepG2 cells
    Sola-Leyva, Alberto
    Lopez-Cara, Luisa C.
    Rios-Marco, Pablo
    Rios, Antonio
    Marco, Carmen
    Carrasco-Jimenez, Maria P.
    [J]. SCIENTIFIC REPORTS, 2019, 9 (1)
  • [5] Choline kinase inhibitors EB-3D and EB-3P interferes with lipid homeostasis in HepG2 cells
    Alberto Sola-Leyva
    Luisa C. López-Cara
    Pablo Ríos-Marco
    Antonio Ríos
    Carmen Marco
    María P. Carrasco-Jiménez
    [J]. Scientific Reports, 9
  • [6] Novel STAT3 Inhibitor Exerts Anti-breast Cancer Effects Both in vitro and in vivo
    Liu, Zhe
    Sun, Yiming
    Yu, Meiling
    Huang, Yingying
    Ma, Liang
    Kong, Lingti
    [J]. LETTERS IN DRUG DESIGN & DISCOVERY, 2023, 20 (12) : 2070 - 2079
  • [7] SU11248 is a novel FLT3 tyrosine kinase inhibitor with potent activity in vitro and in vivo
    O'Farrell, AM
    Abrams, TJ
    Yuen, HA
    Ngai, TJ
    Louie, SG
    Yee, KWH
    Wong, LM
    Hong, W
    Lee, LB
    Town, A
    Smolich, BD
    Manning, WC
    Murray, LJ
    Heinrich, MC
    Cherrington, JM
    [J]. BLOOD, 2003, 101 (09) : 3597 - 3605
  • [8] Ecubectedin is a novel transcriptional inhibitor that displays potent antitumor effects in vitro and in vivo
    Nunez, Gema Santamaria
    Diez, Marta Martinez
    Guillen, Maria Jose
    Garrido-Martin, Eva Maria
    Aviles, Pablo
    Cuevas, Carmen
    [J]. CANCER RESEARCH, 2023, 83 (07)
  • [9] In vitro and in vivo characterization of a potent tyrosine kinase inhibitor that modulates angiogenesis and cancer cell proliferation
    Heise, C
    Wiesmann, M
    Vora, J
    Lee, S
    Renhowe, P
    Harrison, S
    Samara, E
    Hibner, B
    Harris, A
    [J]. EUROPEAN JOURNAL OF CANCER, 2002, 38 : S61 - S62
  • [10] The effects of CEP-37440, an inhibitor of focal adhesion kinase, in vitro and in vivo on inflammatory breast cancer cells
    Salem, Israa
    Alsalahi, Manal
    Chervoneva, Inna
    Aburto, Lucy D.
    Addya, Sankar
    Ott, Gregory R.
    Ruggeri, Bruce A.
    Cristofanilli, Massimo
    Fernandez, Sandra V.
    [J]. BREAST CANCER RESEARCH, 2016, 18
12345