Electroformation of Peptide Self-Assembled Monolayers on Gold

被引:11
|
作者
Bolduc, Olivier R. [1 ]
Correia-Ledo, Debby [1 ]
Masson, Jean-Francois [1 ]
机构
[1] Univ Montreal, Dept Chim, Montreal, PQ H3C 3J7, Canada
基金
加拿大创新基金会; 加拿大自然科学与工程研究理事会;
关键词
SURFACE-PLASMON RESONANCE; NONSPECIFIC ADSORPTION; PROTEIN ADSORPTION; RESIST; FILMS; SAMS; DEPOSITION; SENSORS; PEG;
D O I
10.1021/la203493v
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The application of a potential to deposit a monolayer of 3-mercaptopropionic acid-histidinyl-histidinyl-histidinyl-aspartyl-aspartyl (3-MPA-HHHDD-OH) controls the density and molecular structure of the peptide monolayer, which results in different wettabilities of the surface, surface density, orientation of the molecule (extended or bent), and nonspecific adsorption of serum proteins. 3-MPA-HHHDD-OH must be deposited at 200 mV to maintain an extended configuration, which promoted low biofouling properties.
引用
收藏
页码:22 / 26
页数:5
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