The Cystine-Glutamate Transporter System Xc- Mediates Chemoresistance and the Cancer Stem Cell Phenotype in Glioblastoma Multiforme

被引:0
|
作者
Polewski, Monika Dagmara [1 ,2 ]
Reveron, Rosyli Francis [1 ,3 ]
Cherryholmes, Gregory Allan [1 ,2 ]
Aboody, Karen Saida [1 ,2 ]
机构
[1] City Hope Natl Med Ctr, City Hope, NY USA
[2] Beckman Res Inst, Hope City, NY USA
[3] Calif State Univ San Bernardino, San Bernardino, CA 92407 USA
关键词
D O I
10.1016/j.freeradbiomed.2014.10.205
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
308
引用
收藏
页码:S129 / S130
页数:2
相关论文
共 26 条
  • [1] Glioblastoma Multiforme Utilizes System Xc- in Redox, Survival, and Chemoresistance
    Polewski, Monika Dagmara
    Reveron, Rosyli
    Cherryholmes, Gregory Allan
    Aboody, Karen Saida
    FREE RADICAL BIOLOGY AND MEDICINE, 2013, 65 : S23 - S23
  • [2] The cystine-glutamate antiporter system xc- drives tumor cell glutamate release and cancer-induced bone pain
    Slosky, L.
    BassiriRad, N.
    Symons-Liguori, A.
    Forte, B.
    Bui, L.
    Largent-Milnes, T.
    Vanderah, T.
    JOURNAL OF PAIN, 2015, 16 (04): : S45 - S45
  • [3] Distribution of cystine/glutamate exchange transporter, system xc-, in the mouse brain
    Sato, H
    Tamba, M
    Okuno, S
    Sato, K
    Keino-Masu, K
    Masu, M
    Bannai, S
    JOURNAL OF NEUROSCIENCE, 2002, 22 (18): : 8028 - 8033
  • [4] Role of cystine/glutamate transporter, system xc-, on NO release from macrophages
    Kobayashi, S.
    Sambe, Y.
    Tsutsui, T.
    Bannai, S.
    Sato, H.
    FREE RADICAL BIOLOGY AND MEDICINE, 2012, 53 : S184 - S185
  • [5] Characterization of Select Lysine Mutations of the Cystine/Glutamate Transporter, System xc-
    Koppin, Anna
    Buck, Claire
    Gibson, Amanda
    Chase, Leah
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2023, 299 (03) : S430 - S430
  • [6] Glioblastoma multiforme utilizes system Xc- in survival under oxidative stress and chemoresistance
    Reveron, Rosyli F.
    Polewski, Monika D.
    Aboody, Karen S.
    CANCER RESEARCH, 2014, 74 (19)
  • [7] Cystine-glutamate transporter SLC7A11 in cancer chemosensitivity and chemoresistance
    Huang, Y
    Dai, ZY
    Barbacioru, C
    Sadée, W
    CANCER RESEARCH, 2005, 65 (16) : 7446 - 7454
  • [8] Expression of the activity of cystine/glutamate exchange transporter, system xc-, by xCT and rBAT
    Wang, HY
    Tamba, M
    Kimata, M
    Sakamoto, K
    Bannai, S
    Sato, H
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2003, 305 (03) : 611 - 618
  • [9] System xc- and glutamate transporter inhibition mediates microglial toxicity to oligodendrocytes
    Domercq, Maria
    Sanchez-Gomez, Maria Victoria
    Sherwin, Catherine
    Etxebarria, Estibaliz
    Fern, Robert
    Matute, Carlos
    JOURNAL OF IMMUNOLOGY, 2007, 178 (10): : 6549 - 6556
  • [10] Induction of cystine-glutamate transporter xc- by human immunodeficiency virus type 1 transactivator protein Tat in retinal pigment epithelium
    Bridges, CC
    Hu, HK
    Miyauchi, S
    Siddaramappa, UN
    Ganapathy, ME
    Ignatowicz, L
    Maddox, DM
    Smith, SB
    Ganapathy, V
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2004, 45 (09) : 2906 - 2914