The effect of UV irradiation oil the binding of anticancer drug doxorubicin to DNA in the presence of TiO2 nanoparticles:: Binding drug to DNA

被引：0
|
作者：
Song, Min [1 ]
Wang, Xuemei [1 ]
机构：
[1] Southeast Univ, State Key Lab Bioelect Chien Shiung Wu Lab, Nanjing 210096, Peoples R China
来源：
2006 INTERNATIONAL CONFERENCE ON BIOMEDICAL AND PHARMACEUTICAL ENGINEERING, VOLS 1 AND 2 | 2006年
基金：
美国国家科学基金会;
关键词：
blomolecular recognition; DNA; doxorubicin; nano TiO2; UV irradiation; electrochemistry;
D O I：
暂无
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
The considerable effect of titanium dioxide (TiO2) nanoparticles and UV irradiation on the biomolecular binding behavior of anticancer drug doxorubicin has been studied by using electrochemical methods. Our observations demonstrate that the combination of nano TiO2 and UV irradiation could facilitate the respective DNA binding affinity of anticancer agent and significantly enhance the detection sensitivity for the relative biomolecular recognition process.
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页码：20 / +
页数：2
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