The effect of UV irradiation oil the binding of anticancer drug doxorubicin to DNA in the presence of TiO2 nanoparticles:: Binding drug to DNA

被引：0
|
作者：
Song, Min [1 ]
Wang, Xuemei [1 ]
机构：
[1] Southeast Univ, State Key Lab Bioelect Chien Shiung Wu Lab, Nanjing 210096, Peoples R China
来源：
2006 INTERNATIONAL CONFERENCE ON BIOMEDICAL AND PHARMACEUTICAL ENGINEERING, VOLS 1 AND 2 | 2006年
基金：
美国国家科学基金会;
关键词：
blomolecular recognition; DNA; doxorubicin; nano TiO2; UV irradiation; electrochemistry;
D O I：
暂无
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
The considerable effect of titanium dioxide (TiO2) nanoparticles and UV irradiation on the biomolecular binding behavior of anticancer drug doxorubicin has been studied by using electrochemical methods. Our observations demonstrate that the combination of nano TiO2 and UV irradiation could facilitate the respective DNA binding affinity of anticancer agent and significantly enhance the detection sensitivity for the relative biomolecular recognition process.
引用
收藏
页码：20 / +
页数：2
相关论文
共 50 条
  • [1] Quantifying Anticancer Drug Doxorubicin Binding to DNA using Optical Tweezers
    Ells, Zachary
    Dolle, Brian
    Paramanathan, Thayaparan
    BIOPHYSICAL JOURNAL, 2019, 116 (03) : 506A - 506A
  • [2] The amplification effect of functionalized gold nanoparticles on the binding of anticancer drug dacarbazine to DNA and DNA bases
    Shen, Qin
    Wang, Xuemei
    Fu, Degang
    APPLIED SURFACE SCIENCE, 2008, 255 (02) : 577 - 580
  • [3] Pentoxifylline as a modulator of anticancer drug doxorubicin. Part I: Reduction of doxorubicin DNA binding
    Golunski, Grzegorz
    Borowik, Agnieszka
    Wyrzykowski, Dariusz
    Woziwodzka, Anna
    Piosik, Jacek
    CHEMICO-BIOLOGICAL INTERACTIONS, 2015, 242 : 291 - 298
  • [4] PLATINUM ANTICANCER DRUG-BINDING TO DNA
    LIPPARD, SJ
    FEDERATION PROCEEDINGS, 1986, 45 (06) : 1628 - 1628
  • [5] Binding Parameters of Magnetite Nanoparticles Interaction with Anticancer Drug Doxorubicin
    Bereznyak, Ekaterina G.
    Dukhopelnikov, Evgen V.
    Pesina, Daryna A.
    Gladkovskaya, Natalia A.
    Vakula, Arthur S.
    Kalmykova, Tatyana D.
    Tarapov, Sergey I.
    Polozov, Stanislav D.
    Krasnoselsky, Nikolay V.
    Belous, Anatoliy G.
    Solopan, Sergey A.
    BIONANOSCIENCE, 2019, 9 (02) : 406 - 413
  • [6] Binding Parameters of Magnetite Nanoparticles Interaction with Anticancer Drug Doxorubicin
    Ekaterina G. Bereznyak
    Evgen V. Dukhopelnikov
    Daryna A. Pesina
    Natalia A. Gladkovskaya
    Arthur S. Vakula
    Tatyana D. Kalmykova
    Sergey I. Tarapov
    Stanislav D. Polozov
    Nikolay V. Krasnoselsky
    Anatoliy G. Belous
    Sergey A. Solopan
    BioNanoScience, 2019, 9 : 406 - 413
  • [7] Review on the binding of anticancer drug doxorubicin with DNA and tRNA: Structural models and antitumor activity
    Agudelo, D.
    Bourassa, P.
    Berube, G.
    Tajmir-Riahi, H. A.
    JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY, 2016, 158 : 274 - 279
  • [8] Effect of TiO2 nanoparticles on the thermal stability of native DNA under UV irradiation
    Evgeniya Usenko
    Alexander Glamazda
    Vladimir Valeev
    Anastasiia Svidzerska
    Sergey Anna Laguta
    Victor Petrushenko
    Applied Physics A, 2022, 128
  • [9] Effect of TiO2 nanoparticles on the thermal stability of native DNA under UV irradiation
    Usenko, Evgeniya
    Glamazda, Alexander
    Valeev, Vladimir
    Svidzerska, Anastasiia
    Laguta, Anna
    Petrushenko, Sergey
    Karachevtsev, Victor
    APPLIED PHYSICS A-MATERIALS SCIENCE & PROCESSING, 2022, 128 (10):
  • [10] COOPERATIVITY AND ALLOSTERISM IN THE BINDING OF THE ANTICANCER DRUG DHAQ TO DNA
    ROSENBERG, LS
    KRUGH, TR
    BIOPHYSICAL JOURNAL, 1982, 37 (02) : A294 - A294
12345