Peptide segments ligation and synthesis of peptide thioester and peptide aldehyde

被引：0

作者：

Ma, U ^{[1
]}

Zhao, YF ^{[1
]}

机构：

[1] Tsinghua Univ, Sch Life Sci & Engn, Dept Chem, Bioorgan Phosphorus Chem Key Lab Minist Educ, Beijing 100084, Peoples R China

来源：

PROGRESS IN CHEMISTRY | 2003年 / 15卷 / 05期

关键词：

peptide; protein; segment ligation; peptide thioester; peptide aldehyde;

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

This review focuses on peptide segment ligation for synthesis of peptides and proteins. Ligation is a new methodology in peptide and protein synthesis chemistry. Peptide and protein can be obtained with high yield in aqueous buffer by coupling unprotected peptide segments without activation by enzymatic or chemical agents. The synthetic methods of peptide thioester and peptide aldehyde are also discussed.

引用

页码：393 / 400

页数：8

共 54 条

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