(±)-2-Benzoyl-8-ethyl-1,2-dihydro-isoquinoline-1-carbonitrile:: an original Reissert compound

被引：0
|
作者：
Graulich, A.
Norberg, Bernadette
Liegeois, J.-F.
Wouters, Johan
机构：
[1] Univ Namur, Dept Chem, B-5000 Namur, Belgium
[2] Univ Liege, Drug Res Ctr, Med Chem Lab, B-4000 Liege, Belgium
来源：
ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS | 2007年 / 63卷
关键词：
D O I：
10.1107/s1600536807027729
中图分类号：
O7 [晶体学];
学科分类号：
0702 ; 070205 ; 0703 ; 080501 ;
摘要：
The title compound, C19H16N2O, is a Reissert compound. The heterocyclic fragment of the molecule exhibits a 1,3-diplanar conformation. The phenyl ring is connected to the isoquinoline ring system via an amide bond that adopts an anti conformation with respect to the adjacent C-N bond in the adjacent heterocyclic ring. Intra-and intermolecular C-H center dot center dot center dot O hydrogen bonds are present in the crystal structure.
引用
收藏
页码：O3161 / U3073
页数：10
相关论文
共 50 条
  • [1] Synthesis of chiral N-protected 1,2-dihydro-quinoline-2-carbonitrile and 1,2-dihydro-isoquinoline-1-carbonitrile via an asymmetric Reissert reaction
    Pauvert, M
    Collet, SC
    Bertrand, MJ
    Guingant, AY
    Evain, M
    TETRAHEDRON LETTERS, 2005, 46 (17) : 2983 - 2987
  • [2] REGIOSELECTIVITY IN ALKYLATION OF 1-BENZOYL-1,2-DIHYDROQUINALDONITRILE (QUINOLINE REISSERT COMPOUND)
    GIBSON, HW
    GUILANI, B
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1988, 195 : 473 - ORGN
  • [3] PURINES .8. REACTIONS OF 1-BENZOYL-1,6-DIHYDRO-9-PHENYL-9H-PURINE-6-CARBONITRILE (9-PHENYLPURINE REISSERT COMPOUND) WITH ACID, BASES, AND ELECTROPHILES
    TANJI, K
    SATO, S
    MIYASHITA, A
    OISHI, E
    HIGASHINO, T
    CHEMICAL & PHARMACEUTICAL BULLETIN, 1989, 37 (01) : 187 - 189
  • [4] REISSERT COMPOUND STUDIES .16. REACTION OF 2-BENZOYL-1,2-DIHYDROISOQUINALDONITRILE WITH LACTONES
    WEFER, JM
    POPP, FD
    JOURNAL OF ORGANIC CHEMISTRY, 1967, 32 (06): : 1999 - &
  • [5] REISSERT COMPOUND STUDIES .13. MODEL REACTIONS BASED ON 2-BENZOYL-1,2-DIHYDROISOQUINALDONITRILE
    GIBSON, HW
    POPP, FD
    JOURNAL OF THE CHEMICAL SOCIETY C-ORGANIC, 1966, (20): : 1860 - &
  • [6] STRUCTURE OF 2-BENZOYL-1,2-DIHYDRO-1-ISOQUINOLINECARBONITRILE
    TYKARSKA, E
    JASKOLSKI, M
    KOSTURKIEWICZ, Z
    ACTA CRYSTALLOGRAPHICA SECTION C-CRYSTAL STRUCTURE COMMUNICATIONS, 1985, 41 : 1792 - 1794
  • [7] The catalytic hydration of 1-cyan-2-benzoyl-1, 2-dihydro-isoquinolin (Reissert bodies from isoquinolin)
    Rupe, H
    Frey, W
    HELVETICA CHIMICA ACTA, 1939, 22 : 673 - 683
  • [8] The catalytic hydrogenation of 1-benzoyl-2cyan-1,2-dihydroquinoline. (Reissert body) I
    Rupe, H
    Paltzer, R
    Engel, K
    HELVETICA CHIMICA ACTA, 1937, 20 : 209 - 218
  • [9] STRUCTURE OF ETHYL 1-CYANO-1,2-DIHYDRO-2-ISOQUINOLINECARBOXYLATE
    TYKARSKA, E
    JASKOLSKI, M
    KOSTURKIEWICZ, Z
    ACTA CRYSTALLOGRAPHICA SECTION C-CRYSTAL STRUCTURE COMMUNICATIONS, 1986, 42 : 738 - 740
  • [10] 2,3-Dihydro-1H-pyrrolo[1,2-a]indole-9-carbonitrile
    Madeley, Lee G.
    Lemmerer, Andreas
    Michael, Joseph P.
    ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2012, 68 : O3306 - +
12345