Combined monitoring of intracranial pressure and bispectral index in patients with severe craniocerebral trauma post-operatively

Objective: To investigate the value of simultaneous bispectral index (BIS) and intracranial pressure (ICP) monitoring to evaluate postoperative consciousness and short-term prognosis in patients with severe traumatic brain injury. Methods: We evaluated 30 brain trauma coma patients in the People's Hospital of Northern Jiangsu Province from January 2014 to December 2014 and evaluated Glasgow Coma Scale (GCS) scores at 8-h intervals for 3 days after surgery. BIS and ICP values were recorded at the same time. Based on the GCS score, patients were divided into two groups: group A (GCS score 3-<= 5) and group B (>5-<= 8). Natural survival rates were analyzed statistically and compared between groups. Results: Chi-square testing revealed a significant difference in survival rates between the groups (P < 0.05). Spearman's rank correlation analysis revealed that BIS value was positively correlated with coma degree post-operatively in patients with severe traumatic brain injury, and negatively correlated with ICP values (r = 0.532, P < 0.05; r = 0.521, P < 0.05, respectively). Conclusion: In patients with severe craniocerebral injury, higher severity, higher ICP, and lower BIS were associated with a worse prognosis. Combined monitoring of BIS and ICP is very useful when evaluating the coma degree and prognosis of patients with severe craniocerebral injury post-operatively. (C) 2016 Published by Elsevier B.V.