THE UTILITY OF LIVER SPHEROIDS IN ADDRESSING CURRENT ISSUES IN DRUG METABOLISM AND LIVER TOXICITY EVALUATIONS

被引:0
|
作者
Gan, Jinping [1 ]
机构
[1] Bristol Myers Squibb Co, New York, NY 10154 USA
关键词
D O I
10.1016/j.dmpk.2018.09.048
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
S26
引用
收藏
页码:S10 / S10
页数:1
相关论文
共 50 条
  • [1] Multiscale modelling of drug transport and metabolism in liver spheroids
    Leedale, Joseph A.
    Kyffin, Jonathan A.
    Harding, Amy L.
    Colley, Helen E.
    Murdoch, Craig
    Sharma, Parveen
    Williams, Dominic P.
    Webb, Steven D.
    Bearon, Rachel N.
    INTERFACE FOCUS, 2020, 10 (02)
  • [2] THE UTILITY OF 3D HEPATOCYTE SPHEROIDS IN ADDRESSING MODERN PROBLEMS IN DRUG METABOLISM
    Gan, Jinping
    DRUG METABOLISM AND PHARMACOKINETICS, 2018, 33 (01) : S15 - S15
  • [3] Liver Extracellular Matrices Bioactivated Hepatic Spheroids as a Model System for Drug Hepatotoxicity Evaluations
    Liu, Juan
    Li, Ruihong
    Xue, Rui
    Li, Tingting
    Leng, Ling
    Wang, Yi
    Wang, Jie
    Ma, Jie
    Yan, Jiexin
    Yan, Fang
    Zhang, Youzhi
    Wang, Yunfang
    ADVANCED BIOSYSTEMS, 2018, 2 (10)
  • [4] Drug Metabolism and Toxicity in Chimeric Mice with Humanized Liver
    Emoto, Chie
    Iwasaki, Kazuhide
    Murayama, Node
    Yamazaki, Hiroshi
    JOURNAL OF HEALTH SCIENCE, 2011, 57 (01) : 22 - 27
  • [5] Microfluidic devices for in vitro studies on liver drug metabolism and toxicity
    van Midwoud, Paul M.
    Verpoorte, Elisabeth
    Groothuis, Geny M. M.
    INTEGRATIVE BIOLOGY, 2011, 3 (05) : 509 - 521
  • [6] Utility of endoscopic evaluations in liver transplant candidates
    Weller, DA
    DeGuide, JJ
    Riegler, JL
    AMERICAN JOURNAL OF GASTROENTEROLOGY, 1998, 93 (08): : 1346 - 1350
  • [7] LIVER AND DRUG METABOLISM
    DARNIS, F
    CAHIERS DE MEDECINE, 1974, 15 (10): : 637 - 643
  • [8] Drug Metabolism in the Liver
    Almazroo, Omar Abdulhameed
    Miah, Mohammad Kowser
    Venkataramanan, Raman
    CLINICS IN LIVER DISEASE, 2017, 21 (01) : 1 - +
  • [9] Metabolism and liver toxicity of cannabidiol
    Chen, Si
    Li, Yuxi
    Li, Xilin
    Wu, Qiangen
    Puig, Montserrat
    Moulin, Frederic
    Gingrich, Jeremy
    Guo, Lei
    JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART C-TOXICOLOGY AND CARCINOGENESIS, 2024, 42 (03): : 238 - 254
  • [10] Microfabricated liver for metabolism and toxicity
    Griffith, L
    Sivaraman, A
    Domansky, K
    Tannenbaum, SR
    Capitano, A
    Roberts, J
    CHEMICAL RESEARCH IN TOXICOLOGY, 2002, 15 (12) : 1657 - 1657