Temperaments x genes in bipolar I and bipolar II disorder patients

被引：14
|
作者：
Lin, Ching-I [1 ]
Lee, Sheng-Yu [4 ]
Chang, Yun-Hsuan [2 ,3 ]
Wu, Jo Yung-Wei [2 ]
Wu, Yi-Syuan [1 ]
Wu, Pei-Lin [1 ]
Chen, Hui-Chun [1 ]
Chen, Shiou-Lan [3 ]
Lee, I. Hui [3 ,4 ]
Yeh, Tzung Lieh [3 ,4 ]
Yang, Yen Kuang [3 ,4 ]
Ko, Huei-Chen [1 ,2 ]
Lu, Ru-Band [1 ,2 ,3 ,4 ]
机构：
[1] Natl Cheng Kung Univ, Coll Med, Inst Behav Med, Tainan 70428, Taiwan
[2] Natl Cheng Kung Univ, Coll Med, Inst Allied Hlth Sci, Tainan 70428, Taiwan
[3] Natl Cheng Kung Univ, Coll Med, Dept Psychiat, Tainan 70428, Taiwan
[4] Natl Cheng Kung Univ Hosp, Dept Psychiat, Tainan 70428, Taiwan
来源：
PSYCHIATRY RESEARCH | 2010年 / 177卷 / 03期
关键词：
DRD3; Novelty seeking; Harm avoidance; Bipolar disorder; DOPAMINE D-3 RECEPTOR; TRIDIMENSIONAL PERSONALITY QUESTIONNAIRE; POLYMORPHISM; SCHIZOPHRENIA; ASSOCIATION; D3; EXPRESSION; DEPRESSION; VARIANTS; FAMILY;
D O I：
10.1016/j.psychres.2010.03.005
中图分类号：
R749 [精神病学];
学科分类号：
100205 ;
摘要：
We found the main effects of harm avoidance temperament in predicting bipolar I and II, but the interaction between novelty seeking and Ser9Gly polymorphisms of dopamine D3 receptor gene was demonstrated in bipolar-I patients only. This study provided evidence that differences existed between BP-I and BPII in gene and temperament interactions. (C) 2010 Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码：364 / 366
页数：3
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