Loss of bile salt export pump (BSEP/ABCB11) protects mice from development of carbon tetrachloride (CCl4) induced hepatic fibrosis

被引:0
|
作者
Fuchs, Claudia [1 ]
Dixon, Emmanuel Dauda [1 ]
Konigshofer, Philipp [1 ,2 ,3 ,4 ,5 ]
Mlitz, Veronika [1 ]
Scharnagl, Hubert [6 ]
Stojakovic, Tatjana [7 ]
Reiberger, Thomas [1 ,2 ,3 ,4 ,5 ]
Trauner, Michael [1 ]
机构
[1] Med Univ Vienna, Div Gastroenterol & Hepatol, Internal Med 3, Vienna, Austria
[2] Med Univ Vienna, Vienna Expt Hepat Hemodynam Lab HEPEX, Vienna, Austria
[3] Med Univ Vienna, Christian Doppler Lab Portal Hypertens & Liver Fi, Vienna, Austria
[4] Ludwig Boltzmann Inst Rare & Undiagnosed Dis LBIR, Vienna, Austria
[5] Austrian Acad Sci, CeMM Res Ctr Mol Med, Vienna, Austria
[6] Med Univ Graz, Clin Inst Med & Chem Lab Diagnost, Graz, Austria
[7] Univ Hosp Graz, Clin Inst Med & Chem Lab Diagnost, Graz, Austria
关键词
D O I
暂无
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
FRI158
引用
收藏
页码:S469 / S469
页数:1
相关论文
共 50 条
  • [1] Loss of bile salt export pump (Bsep/Abcb11) aggravates lipopolysaccharide induced hepatic inflammation in mice
    Remetic, Jelena
    Mlitz, Veronika
    Kunczer, Victoria
    Schargl, Hubert
    Stojakovic, Tatjana
    Fuchs, Claudia
    Trauner, Michael
    JOURNAL OF HEPATOLOGY, 2019, 70 (01) : E169 - E169
  • [2] LOSS OF BILE SALT EXPORT PUMP (BSEP/Abcb11) AGGRAVATES LIPOPOLYSACCHARIDE-INDUCED HEPATIC INFLAMMATION IN MICE
    Remetic, Jelena
    Mlitz, Veronika
    Kunczer, Victoria
    Scharnagl, Hubert
    Stojakovic, Tatjana
    Fuchs, Claudia Daniela
    Trauner, Michael H.
    HEPATOLOGY, 2019, 70 : 812A - 813A
  • [3] Recent advances in the exploration of the bile salt export pump (BSEP/ABCB11) function
    Telbisz, Agnes
    Homolya, Laszlo
    EXPERT OPINION ON THERAPEUTIC TARGETS, 2016, 20 (04) : 501 - 514
  • [4] The Canalicular Bile Salt Export Pump BSEP (ABCB11) as a Potential Therapeutic Target
    Stieger, Bruno
    Beuers, Ulrich
    CURRENT DRUG TARGETS, 2011, 12 (05) : 661 - 670
  • [5] OVEREXPRESSION OF THE BILE SALT EXPORT PUMP (ABCB11) IN ABCB4-DEFICIENT MICE AGGRAVATES LIVER FIBROSIS
    Weber, S. N.
    Mahler, M.
    Plantz, V.
    Schmitz, A.
    Lammert, F.
    JOURNAL OF HEPATOLOGY, 2011, 54 : S360 - S360
  • [6] UBIQUITINATION IS ASSOCIATED WITH THE INTERNALIZATION OF BILE SALT EXPORT PUMP (BSEP/ABCB11) FROM THE PLASMA MEMBRANE
    Aida, Kensuke
    Hayashi, Hisamitsu
    Inamura, Kaori
    Mizuno, Tadahaya
    Sugiyama, Yuichi
    HEPATOLOGY, 2011, 54 : 725A - 726A
  • [7] Bile salt export pump (BSEP/ABCB11) can transport a nonbile acid substrate, pravastatin
    Hirano, M
    Maeda, K
    Hayashi, H
    Kusuhara, H
    Sugiyama, Y
    JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2005, 314 (02): : 876 - 882
  • [8] Regulatory mechanisms of the bile salt export pump (BSEP/ABCB11) and its role in related diseases
    Ren, Tengqi
    Pang, Liwei
    Dai, Wanlin
    Wu, Shuodong
    Kong, Jing
    CLINICS AND RESEARCH IN HEPATOLOGY AND GASTROENTEROLOGY, 2021, 45 (06)
  • [9] A novel mutation within a transmembrane helix of the bile salt export pump (BSEP, ABCB11) with delayed development of cirrhosis
    Stindt, Jan
    Ellinger, Philipp
    Weissenberger, Katrin
    Droege, Carola
    Herebian, Diran
    Mayatepek, Ertan
    Homey, Bernhard
    Braun, Stephan
    Esch, Jan Schulte Am
    Horacek, Michael
    Canbay, Ali
    Schmitt, Lutz
    Haeussinger, Dieter
    Kubitz, Ralf
    LIVER INTERNATIONAL, 2013, 33 (10) : 1527 - 1535
  • [10] Production and characterization of feline and canine bile salt export pump (BSEP; ABCB11) containing vesicles
    Van Beusekom, C. D.
    Schrickx, J. A.
    Fink-Gremmels, J.
    JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS, 2012, 35 : 159 - 159