Upper Tract Urothelial Carcinoma: Current Treatment and Outcomes

被引：29
|
作者：
Ristau, Benjamin T. [1 ]
Tomaszewski, Jeffrey J. [1 ]
Ost, Michael C. [1 ]
机构：
[1] Univ Pittsburgh, Med Ctr, Dept Urol, Pittsburgh, PA 15213 USA
来源：
UROLOGY | 2012年 / 79卷 / 04期
关键词：
TRANSITIONAL-CELL CARCINOMA; UPPER URINARY-TRACT; LAPAROSCOPIC RADICAL NEPHROURETERECTOMY; CALMETTE-GUERIN THERAPY; TERM-FOLLOW-UP; OPEN SURGERY; ONCOLOGIC OUTCOMES; RETROPERITONEAL NEPHROURETERECTOMY; URETEROSCOPIC MANAGEMENT; PERCUTANEOUS MANAGEMENT;
D O I：
10.1016/j.urology.2011.12.024
中图分类号：
R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];
学科分类号：
1002 ; 100201 ;
摘要：
The reference standard treatment of upper tract urothelial carcinoma is open radical nephroureterectomy. Many centers have advocated less-invasive treatment modalities. We reviewed contemporary treatments of upper tract urothelial carcinoma and their outcomes. A MEDLINE search was conducted for all relevant published data during the past 15 years. Endoscopic management is feasible for low-grade disease with strict surveillance protocols. Radical nephroureterectomy remains the reference standard for upper tract urothelial carcinoma. The intermediate-term oncologic outcomes are similar between the laparoscopic and open approaches. Controversies still exist regarding the optimal management of the distal ureter, the utility of topical therapy, and the role of lymphadenectomy. UROLOGY 79: 749-756, 2012. (C) 2012 Elsevier Inc.
引用
收藏
页码：749 / 756
页数：8
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