Physiological processes underlying organ injury in alcohol abuse

被引:18
|
作者
Souza-Smith, Flavia M. [1 ]
Lang, Charles H. [2 ]
Nagy, Laura E. [3 ]
Bailey, Shannon M. [4 ]
Parsons, Loren H. [5 ]
Murray, Gary J. [6 ]
机构
[1] Louisiana State Univ, Hlth Sci Ctr, Dept Physiol, 1901 Perdido St, New Orleans, LA 70112 USA
[2] Penn State Coll Med, Dept Cellular & Mol Physiol, Hershey, PA USA
[3] Cleveland Clin Fdn, Dept Pathobiol, Lerner Res Inst, 9500 Euclid Ave, Cleveland, OH 44195 USA
[4] Univ Alabama Birmingham, Dept Pathol, Birmingham, AL 35294 USA
[5] Scripps Res Inst, La Jolla, CA 92037 USA
[6] NIAAA, Bethesda, MD USA
关键词
alcohol; circadian clock; muscle atrophy; adipose tissue; endocannabinoids; MUSCLE PROTEIN-SYNTHESIS; FEAR-POTENTIATED STARTLE; CIRCADIAN TIMING SYSTEM; ACID AMIDE HYDROLASE; WHITE ADIPOSE-TISSUE; SKELETAL-MUSCLE; CHRONIC ETHANOL; ENDOCANNABINOID LEVELS; INDUCED DECREASE; CLOCK GENES;
D O I
10.1152/ajpendo.00270.2016
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
This review summarizes the American Physiological Society (APS) Presidential Symposium 1 entitled "Physiological Processes Underlying Organ Injury in Alcohol Abuse" at the 2016 Experimental Biology meeting. The symposium was organized by Dr. Patricia Molina, past president of the APS, was held on April 3 at the Convention Center in San Diego, CA, and was funded by the National Institute on Alcohol Abuse and Alcoholism. The "Physiological Processes Underlying Organ Injury in Alcohol Abuse Symposium" assembled experts and leaders in the field and served as a platform to discuss and share knowledge on the latest developments and scientific advances on the mechanisms underlying organ injury in alcohol abuse. This symposium provided unique, interdisciplinary alcohol research, including several organs, liver, muscle, adipose, and brain, affected by excessive alcohol use.
引用
收藏
页码:E605 / E619
页数:15
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