The Application of Carbon Nanomaterials in Sensing, Imaging, Drug Delivery and Therapy for Gynecologic Cancers: An Overview

被引:10
|
作者
Xiao, Changji [1 ]
Li, Changming [2 ]
Hu, Jun [1 ]
Zhu, Lirong [1 ]
机构
[1] Peking Univ, Hosp 1, Obstet & Gynaecol Dept, Beijing 100034, Peoples R China
[2] Beijing Technol & Business Univ, Sch Ecol & Environm, State Environm Protect Key Lab Food Chain Pollut, Beijing 100048, Peoples R China
来源
MOLECULES | 2022年 / 27卷 / 14期
关键词
gynecologic cancers; carbon nanomaterials; diagnosis; therapy; clinical application; NANOPARTICLES SUSPENSION INJECTION; OVARIAN-CANCER; MESOPOROUS CARBON; QUANTUM DOTS; IN-VITRO; ULTRASENSITIVE DETECTION; GRAPHENE; NANOTUBES; CELLS; TOXICITY;
D O I
10.3390/molecules27144465
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Gynecologic cancers are one of the main health concerns of women throughout the world, and the early diagnosis and effective therapy of gynecologic cancers will be particularly important for the survival of female patients. As a current hotspot, carbon nanomaterials have attracted tremendous interest in tumor theranostics, and their application in gynecologic cancers has also been developed rapidly with great achievements in recent years. This Overview Article summarizes the latest progress in the application of diverse carbon nanomaterials (e.g., graphenes, carbon nanotubes, mesoporous carbon, carbon dots, etc.) and their derivatives in the sensing, imaging, drug delivery, and therapy of different gynecologic cancers. Important research contributions are highlighted in terms of the relationships among the fabrication strategies, architectural features, and action mechanisms for the diagnosis and therapy of gynecologic cancers. The current challenges and future strategies are discussed from the viewpoint of the real clinical application of carbon-based nanomedicines in gynecologic cancers. It is anticipated that this review will attract more attention toward the development and application of carbon nanomaterials for the theranostics of gynecologic cancers.
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页数:20
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