Gynecologic cancers are one of the main health concerns of women throughout the world, and the early diagnosis and effective therapy of gynecologic cancers will be particularly important for the survival of female patients. As a current hotspot, carbon nanomaterials have attracted tremendous interest in tumor theranostics, and their application in gynecologic cancers has also been developed rapidly with great achievements in recent years. This Overview Article summarizes the latest progress in the application of diverse carbon nanomaterials (e.g., graphenes, carbon nanotubes, mesoporous carbon, carbon dots, etc.) and their derivatives in the sensing, imaging, drug delivery, and therapy of different gynecologic cancers. Important research contributions are highlighted in terms of the relationships among the fabrication strategies, architectural features, and action mechanisms for the diagnosis and therapy of gynecologic cancers. The current challenges and future strategies are discussed from the viewpoint of the real clinical application of carbon-based nanomedicines in gynecologic cancers. It is anticipated that this review will attract more attention toward the development and application of carbon nanomaterials for the theranostics of gynecologic cancers.
机构:
AIST, Hlth Res Inst, Takamatsu, Kagawa 7610395, Japan
Japan Sci & Technol Agcy, PRESTO, Tokyo 3320012, JapanAIST, Hlth Res Inst, Takamatsu, Kagawa 7610395, Japan
机构:
Shenyang Pharmaceut Univ, Sch Pharm, Dept Pharmaceut, Shenyang, Liaoning, Peoples R ChinaShenyang Pharmaceut Univ, Sch Pharm, Dept Pharmaceut, Shenyang, Liaoning, Peoples R China
Zhao, Qinfu
Lin, Yuanzhe
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Shenyang Pharmaceut Univ, Sch Pharm, Dept Pharmaceut, Shenyang, Liaoning, Peoples R ChinaShenyang Pharmaceut Univ, Sch Pharm, Dept Pharmaceut, Shenyang, Liaoning, Peoples R China
Lin, Yuanzhe
Han, Ning
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Beijing Univ Chinese Med, Sch Chinese Mat Med, Dept Chinese Med Pharmaceut, Beijing, Peoples R ChinaShenyang Pharmaceut Univ, Sch Pharm, Dept Pharmaceut, Shenyang, Liaoning, Peoples R China
Han, Ning
Li, Xian
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Shenyang Pharmaceut Univ, Sch Pharm, Dept Pharmaceut, Shenyang, Liaoning, Peoples R ChinaShenyang Pharmaceut Univ, Sch Pharm, Dept Pharmaceut, Shenyang, Liaoning, Peoples R China
Li, Xian
Geng, Hongjian
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Shenyang Pharmaceut Univ, Sch Pharm, Dept Pharmaceut, Shenyang, Liaoning, Peoples R ChinaShenyang Pharmaceut Univ, Sch Pharm, Dept Pharmaceut, Shenyang, Liaoning, Peoples R China
Geng, Hongjian
Wang, Xiudan
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Shenyang Pharmaceut Univ, Sch Pharm, Dept Pharmaceut, Shenyang, Liaoning, Peoples R ChinaShenyang Pharmaceut Univ, Sch Pharm, Dept Pharmaceut, Shenyang, Liaoning, Peoples R China
Wang, Xiudan
Cui, Yu
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Shenyang Pharmaceut Univ, Sch Pharm, Dept Pharmaceut, Shenyang, Liaoning, Peoples R ChinaShenyang Pharmaceut Univ, Sch Pharm, Dept Pharmaceut, Shenyang, Liaoning, Peoples R China
Cui, Yu
Wang, Siling
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Shenyang Pharmaceut Univ, Sch Pharm, Dept Pharmaceut, Shenyang, Liaoning, Peoples R ChinaShenyang Pharmaceut Univ, Sch Pharm, Dept Pharmaceut, Shenyang, Liaoning, Peoples R China