Predicting Response to Growth Hormone Treatment

被引：12
|
作者：
Patel, Leena [1 ]
Clayton, Peter E. [1 ]
机构：
[1] Univ Manchester, Royal Manchester Childrens Hosp, NIHR Greater Manchester Lancashire & S Cumbria Me, Manchester Acad Hlth Sci Ctr,Dept Pediat Endocrin, Manchester M13 9WL, Lancs, England
来源：
INDIAN JOURNAL OF PEDIATRICS | 2012年 / 79卷 / 02期
关键词：
Growth hormone; Growth failure; Growth prediction; Growth hormone response; Molecular biomarkers; FOR-GESTATIONAL-AGE; FACTOR-BINDING PROTEIN-3; SHORT CHILDREN BORN; GH RECEPTOR POLYMORPHISM; I IGF-I; PREPUBERTAL CHILDREN; PROTEOMIC APPROACH; SERUM-LEVELS; INCREASED RESPONSIVENESS; PROMOTER POLYMORPHISM;
D O I：
10.1007/s12098-011-0611-x
中图分类号：
R72 [儿科学];
学科分类号：
100202 ;
摘要：
Despite extensive experience over the past 25 y in managing growth failure with growth hormone (rhGH), predicting treatment efficacy in individual children remains a challenge. In this paper, the authors present the methods that are currently available to clinicians for predicting the growth response, and other more sophisticated techniques which have the potential to pave the way for individualised therapy in the future.
引用
收藏
页码：229 / 237
页数：9
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