Visualization of photoacoustic images in a limited-View measuring system using eigenvalues of a photoacoustic transmission matrix

Photoacoustic imaging is a unique imaging method that involves extracting information from points at different depths, an advantage of ultrasound imaging, while maintaining functional information, a key feature of conventional photo imaging. This makes it easy to add functional images to ultrasound images by adding a laser pulse source to the conventional ultrasound imaging device and detecting a photo-ultrasound signal via a conventional ultrasound probe. One challenge when using normal one-dimensional (1D) probes and generating photoacoustic images is the limited-view problem, in which artefacts are observed due to the positions of the ultrasound transducers. In this study, we used a photoacoustic transmission matrix (PA-TM) for simulation and performed a verification test using a 1D probe and a phantom. The results confirmed that the eigenvalues of the PA-TM visualized the light absorber itself in the limited-view measurement system, which eliminates reconstruction artefacts and further scattering artefacts, and that visualization is possible by signal intensity amplification through further phase modulation. (C) 2017 The Authors. Published by Elsevier GmbH.