Gastric GIST Incidentally Detected on 68Ga-PSMA-PET/CT: Correlation Between Functional Imaging and Histology

被引：14
|
作者：
Vaz, Sofia [1 ]
Oliveira, Carla [1 ]
Castanheira, Joana C. [1 ]
Silva, Angelo F. [1 ]
Costa, Durval C. [1 ]
机构：
[1] Champalimaud Fdn, Dept Nucl Med, Ave Brasilia, P-1400038 Lisbon, Portugal
来源：
CLINICAL NUCLEAR MEDICINE | 2018年 / 43卷 / 12期
关键词：
PSMA PET; CT; prostate cancer; GIST; molecular imaging; PSMA specificity; PSMA expression; GASTROINTESTINAL STROMAL TUMOR; MEMBRANE ANTIGEN; EXPRESSION; PET/CT;
D O I：
10.1097/RLU.0000000000002347
中图分类号：
R8 [特种医学]; R445 [影像诊断学];
学科分类号：
1002 ; 100207 ; 1009 ;
摘要：
Prostate-specific membrane antigen (PSMA) is specific for prostate cancer cells; nevertheless when finding uptake in abnormal locations for prostate cancer metastases, it is important to consider other hypothesis, including second cancers. There are several papers about PSMA expression in many different types of cancer, but few reported expression in gastrointestinal stromal tumors (GIST). In this case, we documented the GIST lesion not only by PET/CT but also by gastroscopy and histology. Additionally, PSMA immunochemistry was performed, showing PSMA expression in tumoral GIST cells (not in endothelial cells), evidencing a good correlation between PET/CT image and histology.
引用
收藏
页码：E488 / E491
页数：4
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