Adult living-related liver donation for acute liver failure: is it ethically appropriate?

被引:4
|
作者
Carlisle, Erica M. [1 ]
Angelos, Peter [1 ,2 ]
Siegler, Mark [2 ]
Testa, Giuliano [1 ]
机构
[1] Univ Chicago, Dept Surg, Med Ctr, Chicago, IL 60637 USA
[2] Univ Chicago, MacLean Ctr Clin Med Eth, Med Ctr, Chicago, IL 60637 USA
关键词
acute liver failure; deceased donor transplantation; ethics; liver transplantation; living organ donor; FULMINANT HEPATIC-FAILURE; QUALITY-OF-LIFE; VANCOUVER FORUM; SINGLE-CENTER; TRANSPLANTATION; DONOR; EXPERIENCE; PANCREAS; OUTCOMES; GRAFT;
D O I
10.1111/j.1399-0012.2011.01413.x
中图分类号
R61 [外科手术学];
学科分类号
摘要
Acute liver failure (ALF) results in the annual death of approximately 3.5 per million people in the United States. Unfortunately, given the marked shortage of cadaveric liver donations and the ethical questions that plague utilization of living donor liver transplantation (LDLT) for ALF, many patients with ALF die before a liver is allocated to them. In this review, we discuss how the consistent utilization of LDLT for ALF could decrease the mortality rate of ALF. Additionally, we examine a key underlying issue: is LDLT for ALF ethically appropriate?
引用
收藏
页码:813 / 820
页数:8
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