Stereoselective and N-terminal selective α-alkylation of peptides using a pyridoxal model compound as a chiral N-terminal activator

被引：11

作者：

Miyashita, K ^{[1
]}

Iwaki, H ^{[1
]}

Tai, K ^{[1
]}

Murafuji, H ^{[1
]}

Imanishi, T ^{[1
]}

机构：

[1] Osaka Univ, Grad Sch Pharmaceut Sci, Osaka 5650871, Japan

来源：

CHEMICAL COMMUNICATIONS | 1998年 / 18期

关键词：

D O I：

10.1039/a805596c

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Stereoselective and N-terminal selective alpha-alkylation of peptides is achieved using a pyridoxal model compound as an N-terminal activator which also functions as a chiral auxiliary.

引用

页码：1987 / 1988

页数：2

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