Discordant HHV8 detection in a young HIV-negative patient with Kaposi's sarcoma and sarcoidosis

被引：15
|
作者：
di Gennaro, G
Canzonieri, V
Schioppa, O
Nasti, G
Carbone, A
Tirelli, U
机构：
[1] Natl Canc Inst, Div Med Oncol A, I-33081 Aviano, Italy
[2] Natl Canc Inst, Div Pathol, Aviano, Italy
来源：
CLINICAL INFECTIOUS DISEASES | 2001年 / 32卷 / 07期
关键词：
D O I：
10.1086/319603
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Human herpesvirus 8 (HHV8), which has been suggested as the causal agent of Kaposi's sarcoma (KS), has also been implicated in the pathogenesis of sarcoidosis. We describe a patient affected concomitantly by sarcoidosis and KS. HHV8 sequences were detected with PCR only on KS lesions, whereas sarcoid tissues did not harbor HHV8 DNA. Immune dysfunction related to sarcoidosis may have facilitated the oncogenic role of HHV8 and the development of KS.
引用
收藏
页码：1100 / 1102
页数：3
相关论文
共 50 条
  • [1] Molecular Features of HHV8 Monoclonal Microlymphoma Associated with Kaposi Sarcoma and Multicentric Castleman Disease in an HIV-Negative Patient
    Rogges, Evelina
    Pelliccia, Sabrina
    Savio, Camilla
    Lopez, Gianluca
    Della Starza, Irene
    La Verde, Giacinto
    Di Napoli, Arianna
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2024, 25 (07)
  • [2] Oral Kaposi's sarcoma in a HIV-negative young patient
    Lombardi, Niccolo
    Varoni, Elena
    Sardella, Andrea
    Lodi, Giovanni
    ORAL ONCOLOGY, 2020, 103
  • [3] HHV8 is not limited to Kaposi's sarcoma
    Pantanowitz, L
    Pinkus, GS
    Dezube, BJ
    Tahan, SR
    MODERN PATHOLOGY, 2005, 18 (08) : 1148 - 1148
  • [4] HHV8 and female Kaposi's sarcoma
    Kennedy, MM
    Lucas, SB
    RussellJones, R
    Howells, DD
    Picton, SJ
    Bardon, A
    Comley, IL
    McGee, JO
    OLeary, JJ
    JOURNAL OF PATHOLOGY, 1997, 183 (04): : 447 - 452
  • [5] HHV8 is not limited to Kaposi's sarcoma - Reply
    Patel, RM
    Goldblum, JR
    Hsi, ED
    MODERN PATHOLOGY, 2005, 18 (08) : 1149 - 1150
  • [6] Acquired Haemophilia A and Kaposi's Sarcoma in an HIV-Negative, HHV-8-Positive Patient: A Discussion of Mechanism and Aetiology
    Cashin, Peter
    Lundberg, Lars Goran
    Hagberg, Hans
    Ejerblad, Elisabeth
    Karlbom, Urban
    ACTA HAEMATOLOGICA, 2010, 124 (01) : 40 - 43
  • [7] Identification of HHV8 in early Kaposi's sarcoma: implications for Kaposi's sarcoma pathogenesis
    Kennedy, MM
    Cooper, K
    Howells, DD
    Picton, S
    Biddolph, S
    Lucas, SB
    McGee, JO
    O'Leary, JJ
    JOURNAL OF CLINICAL PATHOLOGY-MOLECULAR PATHOLOGY, 1998, 51 (01): : 14 - 20
  • [8] Tertiary syphilis and Kaposi sarcoma mistaken for systemic sarcoidosis in an HIV-negative patient
    Anyasodor, M. C.
    Bewley, A.
    BRITISH JOURNAL OF DERMATOLOGY, 2015, 173 (06) : 1501 - 1504
  • [9] HHV8 and Kaposi's sarcoma: A time cohort study
    Kennedy, MM
    Lucas, SB
    Jones, RR
    Howells, DD
    Picton, SJ
    Hanks, EE
    McGee, JOD
    OLeary, JJ
    JOURNAL OF CLINICAL PATHOLOGY-MOLECULAR PATHOLOGY, 1997, 50 (02): : 96 - 100
  • [10] HIV-negative patient with HHV-8 DNA follicular B-cell lymphoma associated with Kaposi's sarcoma
    Robert, C
    Agbalika, F
    Blanc, F
    Dubertret, L
    LANCET, 1996, 347 (9007): : 1042 - 1043
12345