Stereoselective synthesis of the C3-C15 fragment of callyspongiolide

被引：7

作者：

Ramidi, Gopal Reddy ^{[1
,2
]}

Yadav, Jhillu S. ^{[3
]}

Mohapatra, Debendra K. ^{[1
,2
]}

机构：

[1] Indian Inst Chem Technol, CSIR, Organ Synth & Proc Chem Div, Hyderabad 500007, Andhra Pradesh, India

[2] Acad Sci & Innovat Res AcSIR, Mathura Rd, New Delhi 110025, India

[3] Indrashil Univ, Sch Sci, Kadi 382740, Gujarat, India

来源：

TETRAHEDRON LETTERS | 2018年 / 59卷 / 39期

关键词：

Callyspongiolide; Natural products; Julia-Kocienski olefination; Brown asymmetric allylation; Base-induced elimination reaction; CYCLIC ACID ANHYDRIDES; ENANTIOSELECTIVE SYNTHESIS; ASYMMETRIC ALLYLBORATION; CYTOTOXIC MACROLIDE; ALCOHOLS; CONDENSATION; OXIDATION; LACTONES; LIPASE;

D O I：

10.1016/j.tetlet.2018.08.041

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The synthesis of C3-C15 fragment of callyspongiolide, a 14-membered macrolides isolated from the marine sponge Callyspongia sp., which was collected from the Indonesia, is reported. Highlights of the synthesis include construction of E-olefin through Julia-Kocienski olefination, Brown asymmetric allylation and base-induced elimination reactions for propargyl alcohol synthesis. (C) 2018 Published by Elsevier Ltd.

引用

页码：3579 / 3582

页数：4