New terpenoids, olibanumols D-G, from traditional Egyptian medicine olibanum, the gum-resin of Boswellia carterii

被引：29
|
作者：
Morikawa, Toshio [1 ,2 ]
Oominami, Hideo [1 ]
Matsuda, Hisashi [1 ]
Yoshikawa, Masayuki [1 ]
机构：
[1] Kyoto Pharmaceut Univ, Yamashina Ku, Kyoto 6078412, Japan
[2] Kinki Univ, Pharmaceut Res & Technol Inst, Osaka 5778502, Japan
来源：
JOURNAL OF NATURAL MEDICINES | 2011年 / 65卷 / 01期
关键词：
Olibanumol; Olibanum; Boswellia carterii; Nitric oxide production inhibitory activity; Burseraceae; NITRIC-OXIDE PRODUCTION; INHIBITORS;
D O I：
10.1007/s11418-010-0472-z
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
A new prenylaromadendrane-type diterpene, olibanumol D (1), and three new oleanane- and lupane-type triterpenes, olibanumols E (2), F (3), and G (4), were isolated from the traditional Egyptian medicine olibanum, the exuded gum-resin from Boswellia carterii Birdw. Their structures were established mainly on the basis of 1D and 2D NMR spectral data. Compounds 1 and 2 exhibited nitric oxide production inhibitory activity in lipopolysaccharide-activated mouse peritoneal macrophages.
引用
收藏
页码：129 / 134
页数：6
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