Antithrombotic Treatment in Elderly Patients with Atrial Fibrillation

被引：10

作者：

Suarez Fernandez, C. ^{[1
]}

Camafort, M. ^{[2
]}

Cepeda Rodrigo, J. M. ^{[3
]}

Diez-Manglano, J. ^{[4
]}

Formiga, F. ^{[5
]}

Reino, A. Pose ^{[6
]}

Tiberio, G. ^{[7
]}

Mostaza, J. M.

机构：

[1] Hosp Univ La Princesa, Grp Riesgo Vasc, SEMI, Madrid, Spain

[2] Hosp Clin Barcelona, Grp Riesgo Vasc, SEMI, Barcelona, Spain

[3] Hosp Vega Baja Orihuela, Grp Riesgo Vasc, SEMI, Alicante, Spain

[4] Hosp Royo Villanova, Grp Riesgo Vasc, SEMI, Zaragoza, Spain

[5] Hosp Univ Bellvitge, Grp Riesgo Vasc, SEMI, Barcelona, Spain

[6] Complexo Hosp Univ Santiago, Grp Riesgo Vasc, SEMI, Santiago De Compostela, Spain

[7] Hosp Virgen del Camino, Grp Riesgo Vasc, SEMI, Pamplona, Spain

[8] Hosp Carlos III, Grp Riesgo Vasc, SEMI, Madrid, Spain

来源：

REVISTA CLINICA ESPANOLA | 2015年 / 215卷 / 03期

关键词：

Elderly; Nonvalvular atrial fibrillation; Guidelines; Vitamin K antagonists; Dabigatran; Rivaroxaban; Apixaban; Edoxaban; STROKE PREVENTION; ORAL ANTICOAGULATION; WARFARIN THERAPY; RISK-FACTORS; PREVALENCE; ADULTS; RECOMMENDATIONS; METAANALYSIS; POPULATION; GUIDELINES;

D O I：

10.1016/j.rce.2014.11.024

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Atrial fibrillation (AF) in the elderly is a complex condition due to the high number of frequently associated comorbidities, such as cardiovascular and kidney disease, cognitive disorders, falls and polypharmacy. Except when contraindicated, anticoagulation is necessary for preventing thromboembolic events in this population. Both vitamin K antagonists and direct oral anticoagulants (dabigatran, rivaroxaban and apixaban) are indicated in this context. Renal function should be closely monitored for this age group when these drugs are used. In recent years, various clinical practice guidelines have been published on patients with AF. The majority of these guidelines make specific recommendations on the clinical characteristics and treatment of elderly patients. In this update, we review the specific comments on the recommendations concerning antithrombotic treatment in elderly patients with nonvalvular AF. (C) 2014 Elsevier Espana, S.L.U. and Sociedad Espanola de Medicina Interna (SEMI). All rights reserved.

引用

页码：171 / 181

页数：11

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