Treatment of meningitis caused by methicillin-resistant Staphylococcus aureus with linezolid

被引：44
|
作者：
Kessler, A. T.
Kourtis, A. P.
机构：
[1] Eastern Virginia Med Sch, Dept Obstet Gynecol, Norfolk, VA 23501 USA
[2] Norside Cherokee Hosp, Atlanta, GA USA
来源：
INFECTION | 2007年 / 35卷 / 04期
关键词：
D O I：
10.1007/s15010-007-6211-z
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
Methicillin-resistant Staphylococcus aureus (MRSA) is increasing in prevalence both in nosocomial and in community settings. Treatment of such infections, particularly in the central nervous system (CNS), is problematic, as available options are limited. Linezolid is a new antibiotic with activity against Gram-positive cocci, including MRSA, and has good penetration into the cerebrospinal fluid. To our knowledge, there are only three case reports of successful treatment of CNS infections caused by MRSA with linezolid; we report herein a fourth such case. Clinical trials to address the role of linezolid in CNS infections are urgently needed.
引用
收藏
页码：271 / 274
页数：4
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