Morphea as a Consequence of Accelerated Partial Breast Irradiation

被引：8

作者：

Wernicke, A. Gabriella ^{[1
]}

Goltser, Yevgeniya ^{[2
]}

Trichter, Samuel ^{[1
]}

Sabbas, Albert ^{[1
]}

Gaan, Jalong ^{[3
]}

Swistel, Alexander J. ^{[4
]}

Magro, Cynthia M. ^{[5
]}

机构：

[1] Cornell Univ, Weil Med Coll, Dept Radiat Oncol, New York, NY 10065 USA

[2] Brandeis Univ, Dept Biol Sci, Waltham, MA USA

[3] Cornell Univ, Weil Med Coll, Dept Dermatol, New York, NY 10065 USA

[4] Cornell Univ, Weil Med Coll, Dept Surg, New York, NY 10065 USA

[5] Cornell Univ, Weil Med Coll, Dept Pathol, New York, NY 10065 USA

来源：

CLINICAL BREAST CANCER | 2011年 / 11卷 / 01期

关键词：

Brachytherapy; Contura; Radiation; Radiotherapy; OF-THE-LITERATURE; ANTIENDOTHELIAL CELL ANTIBODIES; LOCALIZED SCLERODERMA; POSTIRRADIATION MORPHEA; PULMONARY-FIBROSIS; RADIOTHERAPY; RADIATION; CANCER; COMPLICATION; CARCINOMA;

D O I：

10.3816/CBC.2011.n.012

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Morphea is a localized form of scleroderma usually unaccomparied by the typical systemic stigmata that characterize progressive systemics scleroderma. It rarely manifests at the site of whole breast external beam radiation therpay. We present an unusual case of radiation induced morphea (RIM) that occurred after accelerated partial breast irradiation (APBI) using intracavitary contura brachytherapy A 65-year-old white woman was treated forstate IIA invasive ductal carcinoma of the left breast with APBI to a dose of 34 Gy in 34 Gy fractions twice daily over the course 5 days with intracavitary brachytherapy. At 1.5 years after completion of APBI, the patient developed an area of tenderness, erythema, and induration at the site of irradiation. A skin biopsy was consistend with morphea. To our knowledge, this is the first case of RIM confined to the area of APBI

引用

页码：67 / 70

页数：4

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