Cross-phase modulation imaging

被引:18
|
作者
Samineni, Prathyush [1 ]
Li, Baolei [2 ]
Wilson, Jesse W. [1 ]
Warren, Warren S. [1 ,3 ,4 ]
Fischer, Martin C. [1 ]
机构
[1] Duke Univ, Dept Chem, Durham, NC 27708 USA
[2] Duke Univ, Dept Phys, Durham, NC 27708 USA
[3] Duke Univ, Dept Radiol, Durham, NC 27708 USA
[4] Duke Univ, Dept Biomed Engn, Durham, NC 27708 USA
基金
美国国家卫生研究院;
关键词
2-PHOTON ABSORPTION;
D O I
10.1364/OL.37.000800
中图分类号
O43 [光学];
学科分类号
070207 ; 0803 ;
摘要
We demonstrate a cross-phase modulation measurement technique based on the sensitive detection of modulation transfer in a pump-probe setup. By modulating the amplitude of the pump beam and spectrally analyzing the probe beam, we achieve a rapid, background-free measurement of nonlinear phase modulation using power levels acceptable in biological imaging. This measurement technique would allow the extension of widely employed phase microscopy methods to the nonlinear regime, providing intrinsic and universal nonlinear contrast for biological imaging. (C) 2012 Optical Society of America
引用
收藏
页码:800 / 802
页数:3
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