Hepatitis C virus genotypes in hemodialysis patients in Angola

被引：2
|
作者：
da Costa Marques Borges, Luis Filipe [1 ]
Zalis, Mariano Gustavo [1 ,2 ]
Santoro-Lopes, Guilherme [2 ]
Varella, Rafael Brandao [3 ]
机构：
[1] Univ Fed Rio de Janeiro, Hosp Univ Clementino Fraga Filho, Lab Mol Parasitol, Rio De Janeiro, Brazil
[2] Univ Fed Rio de Janeiro, Sch Med, Dept Prevent Med, Rio De Janeiro, Brazil
[3] Univ Fed Fluminense, Dept Microbiol & Parasitol, Rio De Janeiro, Brazil
来源：
JOURNAL OF MEDICAL VIROLOGY | 2019年 / 91卷 / 03期
关键词：
Africa; Angola; epidemiology; genotypes; hemodialysis; hepatitis C virus; B-VIRUS; GLOBAL EPIDEMIOLOGY; RISK-FACTORS; INFECTION; PREVALENCE; AFRICA; LUANDA;
D O I：
10.1002/jmv.25354
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
To our knowledge, there are no published data on hepatitis C virus (HCV) genotypes in Angola. This study aimed at assessing the distribution of HCV genotypes in seropositive hemodialysis patients in Luanda. Among 51 HCV-positive subjects included, viremia was detected in 27 (53%). HCV genotyping was performed by bidirectional sequencing of the 5'-untranslated region by the Sanger method. HCV genotype 4 was largely predominant (20 cases; 74%), followed by genotypes 1b (5 cases; 18.5%), 1a and 2 (one case each; 3.7%). These results suggest that the distribution of HCV genotypes in Angola is similar to that reported from other Central African countries.
引用
收藏
页码：518 / 521
页数：4
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